Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational Study
Objective: This study aimed to determine the relationship between one of the most commonly used anesthesia techniques, ketamine-based sedation, on the value of adenoma detection rate (ADR) during colonoscopy screening. Methods: This prospective, observational study included 140 patients, who underwe...
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| Format: | Article |
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Galenos Publishing House
2022-03-01
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| Series: | Medeniyet Medical Journal |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-75282 |
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| author | Mirza KOVACEVIC Nermina RIZVANOVIC Adisa SABANOVIC ADILOVIC Nedim BARUCIJA Anida ABAZOVIC |
| author_facet | Mirza KOVACEVIC Nermina RIZVANOVIC Adisa SABANOVIC ADILOVIC Nedim BARUCIJA Anida ABAZOVIC |
| author_sort | Mirza KOVACEVIC |
| collection | DOAJ |
| description | Objective: This study aimed to determine the relationship between one of the most commonly used anesthesia techniques, ketamine-based sedation, on the value of adenoma detection rate (ADR) during colonoscopy screening.
Methods: This prospective, observational study included 140 patients, who underwent a standard colonoscopy preparation before the procedure. Sedation regimens included ketamine at 0.5 mg/kg and propofol at 0.5 mg/kg. Additional doses of propofol were administered at 0.5 mg/kg to maintain the Ramsey Sedation scale. Baseline characteristics, ADR, bowel preparation quality according to the Chicago bowel preparation (CHBP) scale, cecal intubation, colonoscopy removal, and complications were analyzed.
Results: The mean age of patients was 55.76 years; 40 (28.6%) were males and 100 (71.4%) were females. The ADR was 43.57%, wherein 15.71% in males and 27.86% in females. There were 43.6% adenomas, 17.9% biopsies, and 22.9% polypectomies. The largest location of adenomas/polyps were in the rectum and sigmoid and ascending colon (p=0.11), a biopsy of the sigmoid colon and ileum (p<0.05), polypectomy of the rectum and sigmoid and ascending colon (p<0.05). The cecal intubation was 93.6% with a withdrawal time that is >6 min in most patients (80%) (p<0.05). The CHBP scale showed good bowel preparation (p<0.05) without complications.
Conclusions: Ketamine-based sedation is in good overall correlation with ADR. Therefore, the sedation technique should be included for ADR assessment in the future. |
| format | Article |
| id | doaj-art-c3c68dc5f968436397e4b1e79d9c0988 |
| institution | Kabale University |
| issn | 2149-2042 2149-4606 |
| language | English |
| publishDate | 2022-03-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Medeniyet Medical Journal |
| spelling | doaj-art-c3c68dc5f968436397e4b1e79d9c09882025-01-30T07:15:46ZengGalenos Publishing HouseMedeniyet Medical Journal2149-20422149-46062022-03-01371798410.4274/MMJ.galenos.2022.75282MEDJ-75282Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational StudyMirza KOVACEVIC0Nermina RIZVANOVIC1Adisa SABANOVIC ADILOVIC2Nedim BARUCIJA3Anida ABAZOVIC4Cantonal Hospital Zenica, Department of Anesthesiology and Intensive Care Unit, Zenica, Bosnia and HerzegovinaCantonal Hospital Zenica, Department of Anesthesiology and Intensive Care Unit, Zenica, Bosnia and HerzegovinaCantonal Hospital Zenica, Department of Anesthesiology and Intensive Care Unit, Zenica, Bosnia and HerzegovinaCantonal Hospital Zenica, Department of Otorhinolaryngology and Maxillofacial Surgery, Zenica, Bosnia and HerzegovinaCantonal Hospital Zenica, Department of Neurology, Zenica, Bosnia and HerzegovinaObjective: This study aimed to determine the relationship between one of the most commonly used anesthesia techniques, ketamine-based sedation, on the value of adenoma detection rate (ADR) during colonoscopy screening. Methods: This prospective, observational study included 140 patients, who underwent a standard colonoscopy preparation before the procedure. Sedation regimens included ketamine at 0.5 mg/kg and propofol at 0.5 mg/kg. Additional doses of propofol were administered at 0.5 mg/kg to maintain the Ramsey Sedation scale. Baseline characteristics, ADR, bowel preparation quality according to the Chicago bowel preparation (CHBP) scale, cecal intubation, colonoscopy removal, and complications were analyzed. Results: The mean age of patients was 55.76 years; 40 (28.6%) were males and 100 (71.4%) were females. The ADR was 43.57%, wherein 15.71% in males and 27.86% in females. There were 43.6% adenomas, 17.9% biopsies, and 22.9% polypectomies. The largest location of adenomas/polyps were in the rectum and sigmoid and ascending colon (p=0.11), a biopsy of the sigmoid colon and ileum (p<0.05), polypectomy of the rectum and sigmoid and ascending colon (p<0.05). The cecal intubation was 93.6% with a withdrawal time that is >6 min in most patients (80%) (p<0.05). The CHBP scale showed good bowel preparation (p<0.05) without complications. Conclusions: Ketamine-based sedation is in good overall correlation with ADR. Therefore, the sedation technique should be included for ADR assessment in the future.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-75282colonoscopysedationadenoma |
| spellingShingle | Mirza KOVACEVIC Nermina RIZVANOVIC Adisa SABANOVIC ADILOVIC Nedim BARUCIJA Anida ABAZOVIC Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational Study Medeniyet Medical Journal colonoscopy sedation adenoma |
| title | Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational Study |
| title_full | Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational Study |
| title_fullStr | Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational Study |
| title_full_unstemmed | Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational Study |
| title_short | Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational Study |
| title_sort | adenoma detection rate in colonoscopic screening with ketamine based sedation a prospective observational study |
| topic | colonoscopy sedation adenoma |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-75282 |
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