The mechanism of NF-κB-TERT feedback regulation of granulosa cell apoptosis in PCOS rats.

The mechanism of NF-κB-TERT feedback regulation of granulosa cell apoptosis in PCOS rats.

Patients with Polycystic ovary syndrome (PCOS) have chronic low-grade ovarian inflammation. Inflammation can cause telomere dysfunction, and telomere and telomerase complex are also involved in regulating inflammation. However, the specific mechanisms of inflammatory signaling feedback and telomere-...

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Main Authors: Haoxuan Xue, Zecheng Hu, Shun Liu, Shun Zhang, Wenqin Yang, Jiasi Li, Chulin Yan, Jiaming Zhang, Jing Zhang, Xiaocan Lei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0312115
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