Naphthoquinone-derived ZSW-4B induces apoptosis in triple-negative breast cancer via AMPK signalling activation

Naphthoquinone-derived ZSW-4B induces apoptosis in triple-negative breast cancer via AMPK signalling activation

Abstract Triple-negative breast cancer (TNBC) is the most malignant molecular subtype of breast cancer and is characterized by aggressiveness, high mortality, significant heterogeneity, and poor prognosis. AMPK plays a critical role in maintaining the cellular energy balance, and its inactivation is...

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Main Authors: Xiyuan Hu, Hongdou Liu, Tiao Luo, Ling Chen, Ting Peng, Min Wen, Wensong Luo, Qunfang Xu, Yuanzhu Xie, Mo Li, Mingquan Liu, Xiaohe Liu, Suyou Liu, Shuaiwen Zhu, Zizheng Zou, Zhiyong Luo
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-79592-9
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