Intravenous Clarithromycin in Critically Ill Adults: A Population Pharmacokinetic Study

Intravenous Clarithromycin in Critically Ill Adults: A Population Pharmacokinetic Study

<b>Background:</b> Clarithromycin is a commonly used macrolide antibiotic. Infection is a major source of mortality and morbidity in critical care units. Pharmacokinetics may vary during critical illness and suboptimal antimicrobial exposure has been shown to be associated with treatment...

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Main Authors: Reya V. Shah, Karin Kipper, Emma H. Baker, Charlotte I. S. Barker, Isobel Oldfield, Harriet C. Davidson, Cleodie C. Swire, Barbara J. Philips, Atholl Johnston, Andrew Rhodes, Mike Sharland, Joseph F. Standing, Dagan O. Lonsdale
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Antibiotics
Subjects:
pharmacometrics
clarithromycin
critical illness
macrolides
Online Access:https://www.mdpi.com/2079-6382/14/6/559
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