Abuse potential of fentanyl and fentanyl analogues
Introduction: In this perspective review, we evaluated the clinical management of fatal fentanyl overdose in several routes of administration, concentrating on both legally prescribed and illegally produced formulations. Methods: A literature search was conducted on Web of Science, PubMed, and Goog...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tabriz University of Medical Sciences
2024-11-01
|
| Series: | BioImpacts |
| Subjects: | |
| Online Access: | https://bi.tbzmed.ac.ir/PDF/bi-14-27691.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832595640200200192 |
|---|---|
| author | Anusha Thumma Kwadwo Mfoafo Niloofar Babanejad Alborz Omidian Yadollah Omidi Hamid Omidian |
| author_facet | Anusha Thumma Kwadwo Mfoafo Niloofar Babanejad Alborz Omidian Yadollah Omidi Hamid Omidian |
| author_sort | Anusha Thumma |
| collection | DOAJ |
| description | Introduction: In this perspective review, we evaluated the clinical management of fatal fentanyl overdose in several routes of administration, concentrating on both legally prescribed and illegally produced formulations. Methods: A literature search was conducted on Web of Science, PubMed, and Google Scholar databases, using the following keywords: fentanyl, illicit fentanyl, deaths, misuse, abuse, and naloxone. We included only articles whose abstracts were available in English. All articles were screened using their abstracts to determine their relevance to the current review. Results: The gold standard for treating both acute and chronic pain is fentanyl, but abuse of the drug has exploded globally since the late 2000s. Fentanyl abuse has been shown to frequently result in serious harm and even death. Conclusions: By educating patients and physicians, making rescue kits easily accessible, developing vaccines to prevent opioid addiction, and perhaps even creating new tamper-resistant fentanyl formulations, it may be possible to prevent fentanyl misuse, therapeutic errors, and the repercussions that follow. |
| format | Article |
| id | doaj-art-c36a8897afc744cbb2a7fdc509998752 |
| institution | Kabale University |
| issn | 2228-5652 2228-5660 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | BioImpacts |
| spelling | doaj-art-c36a8897afc744cbb2a7fdc5099987522025-01-18T10:04:16ZengTabriz University of Medical SciencesBioImpacts2228-56522228-56602024-11-01146276912769110.34172/bi.2024.27691bi-27691Abuse potential of fentanyl and fentanyl analoguesAnusha Thumma0Kwadwo Mfoafo1Niloofar Babanejad2Alborz Omidian3Yadollah Omidi4Hamid Omidian5College of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL, United StatesCollege of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL, United StatesWestchester Medical Center, Department of Psychiatry, Valhalla, NY, United StatesWestchester Medical Center, Department of Psychiatry, Valhalla, NY, United StatesCollege of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL, United StatesCollege of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL, United StatesIntroduction: In this perspective review, we evaluated the clinical management of fatal fentanyl overdose in several routes of administration, concentrating on both legally prescribed and illegally produced formulations. Methods: A literature search was conducted on Web of Science, PubMed, and Google Scholar databases, using the following keywords: fentanyl, illicit fentanyl, deaths, misuse, abuse, and naloxone. We included only articles whose abstracts were available in English. All articles were screened using their abstracts to determine their relevance to the current review. Results: The gold standard for treating both acute and chronic pain is fentanyl, but abuse of the drug has exploded globally since the late 2000s. Fentanyl abuse has been shown to frequently result in serious harm and even death. Conclusions: By educating patients and physicians, making rescue kits easily accessible, developing vaccines to prevent opioid addiction, and perhaps even creating new tamper-resistant fentanyl formulations, it may be possible to prevent fentanyl misuse, therapeutic errors, and the repercussions that follow.https://bi.tbzmed.ac.ir/PDF/bi-14-27691.pdfopioid crisisfentanylillicit fentanylfentanyl analogousfentanyl abuse |
| spellingShingle | Anusha Thumma Kwadwo Mfoafo Niloofar Babanejad Alborz Omidian Yadollah Omidi Hamid Omidian Abuse potential of fentanyl and fentanyl analogues BioImpacts opioid crisis fentanyl illicit fentanyl fentanyl analogous fentanyl abuse |
| title | Abuse potential of fentanyl and fentanyl analogues |
| title_full | Abuse potential of fentanyl and fentanyl analogues |
| title_fullStr | Abuse potential of fentanyl and fentanyl analogues |
| title_full_unstemmed | Abuse potential of fentanyl and fentanyl analogues |
| title_short | Abuse potential of fentanyl and fentanyl analogues |
| title_sort | abuse potential of fentanyl and fentanyl analogues |
| topic | opioid crisis fentanyl illicit fentanyl fentanyl analogous fentanyl abuse |
| url | https://bi.tbzmed.ac.ir/PDF/bi-14-27691.pdf |
| work_keys_str_mv | AT anushathumma abusepotentialoffentanylandfentanylanalogues AT kwadwomfoafo abusepotentialoffentanylandfentanylanalogues AT niloofarbabanejad abusepotentialoffentanylandfentanylanalogues AT alborzomidian abusepotentialoffentanylandfentanylanalogues AT yadollahomidi abusepotentialoffentanylandfentanylanalogues AT hamidomidian abusepotentialoffentanylandfentanylanalogues |