Exploring the occurence and risk factors of post-stroke depression among stroke survivors in Africa: a comprehensive systematic review and meta-analysis
Abstract Background Post-stroke depression is a significant health concern, especially in developing countries. The high prevalence, incidence, and complexity of depression among stroke survivors pose a substantial occurence on vulnerable individuals. This study aimed to investigate the prevalence,...
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BMC
2025-04-01
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| Series: | BMC Public Health |
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| Online Access: | https://doi.org/10.1186/s12889-025-22685-5 |
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| author | Techilo Tinsae Wondale Getinet Setegn Fentahun Shegaye Shumet Girmaw Medifu Fantahun Andualem Girum Nakie Tesfaye Segon Selam Koye Gebresilassie Tadesse Gidey Rtbey |
| author_facet | Techilo Tinsae Wondale Getinet Setegn Fentahun Shegaye Shumet Girmaw Medifu Fantahun Andualem Girum Nakie Tesfaye Segon Selam Koye Gebresilassie Tadesse Gidey Rtbey |
| author_sort | Techilo Tinsae |
| collection | DOAJ |
| description | Abstract Background Post-stroke depression is a significant health concern, especially in developing countries. The high prevalence, incidence, and complexity of depression among stroke survivors pose a substantial occurence on vulnerable individuals. This study aimed to investigate the prevalence, incidence, and risk factors of post-stroke depression among stroke survivors in Africa. Methods PubMed, WHO Global Index Medicus, Web of Science, Cochrane Library, Google Scholar, ScienceDirect, HINARI, and Google were the sources of data searching. Literature reporting the prevalence, incidence and risk factors of post-stroke depression in Africa was included. The quality of each study was evaluated using the Newcastle-Ottawa Quality Assessment Scale (NOS). Data were extracted using a Microsoft Excel spreadsheet, and data analysis was performed using STATA version 11. Heterogeneity between studies was checked using the I2 statistical test. Publication bias was checked using Egger’s statistical test and funnel plot. Results A total of twenty-two relevant studies with 3175 stroke patients were included in this systematic review and meta-analysis. The overall estimated pooled prevalence and incidence of depression among stroke survivors in Africa were found to be 42.5% (95% CI = 26.9, 58.1) and 33.2% (95% CI = 23.3, 43.0), respectively. The subgroup analysis further revealed that Nigeria had the highest prevalence of depression at 47.6% (95% CI: 15.1, 80.1), followed by Ethiopia at 44.4% (95% CI: 28.2, 60.6). This study did not identify any factors that were positively associated with post-stroke depression. Conclusion The prevalence and incidence of depression among stroke survivors are notably high. Despite the high occurence, this study did not identify specific risk factors positively associated with post-stroke depression. Consequently, addressing post-stroke depression through integrated care models, routine screening, and targeted interventions is crucial for enhancing the quality of life and rehabilitation outcomes for stroke survivors in Africa. |
| format | Article |
| id | doaj-art-c3613dd4c12c4dcf9937eea3794a2fbb |
| institution | OA Journals |
| issn | 1471-2458 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMC |
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| series | BMC Public Health |
| spelling | doaj-art-c3613dd4c12c4dcf9937eea3794a2fbb2025-08-20T02:28:42ZengBMCBMC Public Health1471-24582025-04-0125111610.1186/s12889-025-22685-5Exploring the occurence and risk factors of post-stroke depression among stroke survivors in Africa: a comprehensive systematic review and meta-analysisTechilo Tinsae0Wondale Getinet1Setegn Fentahun2Shegaye Shumet3Girmaw Medifu4Fantahun Andualem5Girum Nakie6Tesfaye Segon7Selam Koye8Gebresilassie Tadesse9Gidey Rtbey10College of Medicine and Health Science, Department of Psychiatry, University of GondarCollege of Medicine and Health Science, Department of Psychiatry, University of GondarCollege of Medicine and Health Science, Department of Psychiatry, University of GondarCollege of Medicine and Health Science, Department of Psychiatry, University of GondarCollege of Medicine and Health Science, Department of Psychiatry, University of GondarCollege of Medicine and Health Science, Department of Psychiatry, University of GondarCollege of Medicine and Health Science, Department of Psychiatry, University of GondarDepartment of Psychiatry, Mettu UniversityCollege of Medicine and Health Science, Department of Psychiatry, University of GondarCollege of Medicine and Health Science, Department of Psychiatry, University of GondarCollege of Medicine and Health Science, Department of Psychiatry, University of GondarAbstract Background Post-stroke depression is a significant health concern, especially in developing countries. The high prevalence, incidence, and complexity of depression among stroke survivors pose a substantial occurence on vulnerable individuals. This study aimed to investigate the prevalence, incidence, and risk factors of post-stroke depression among stroke survivors in Africa. Methods PubMed, WHO Global Index Medicus, Web of Science, Cochrane Library, Google Scholar, ScienceDirect, HINARI, and Google were the sources of data searching. Literature reporting the prevalence, incidence and risk factors of post-stroke depression in Africa was included. The quality of each study was evaluated using the Newcastle-Ottawa Quality Assessment Scale (NOS). Data were extracted using a Microsoft Excel spreadsheet, and data analysis was performed using STATA version 11. Heterogeneity between studies was checked using the I2 statistical test. Publication bias was checked using Egger’s statistical test and funnel plot. Results A total of twenty-two relevant studies with 3175 stroke patients were included in this systematic review and meta-analysis. The overall estimated pooled prevalence and incidence of depression among stroke survivors in Africa were found to be 42.5% (95% CI = 26.9, 58.1) and 33.2% (95% CI = 23.3, 43.0), respectively. The subgroup analysis further revealed that Nigeria had the highest prevalence of depression at 47.6% (95% CI: 15.1, 80.1), followed by Ethiopia at 44.4% (95% CI: 28.2, 60.6). This study did not identify any factors that were positively associated with post-stroke depression. Conclusion The prevalence and incidence of depression among stroke survivors are notably high. Despite the high occurence, this study did not identify specific risk factors positively associated with post-stroke depression. Consequently, addressing post-stroke depression through integrated care models, routine screening, and targeted interventions is crucial for enhancing the quality of life and rehabilitation outcomes for stroke survivors in Africa.https://doi.org/10.1186/s12889-025-22685-5DepressionStrokePost-strokePost-stroke depressionPrevalenceIncidence and stroke depression |
| spellingShingle | Techilo Tinsae Wondale Getinet Setegn Fentahun Shegaye Shumet Girmaw Medifu Fantahun Andualem Girum Nakie Tesfaye Segon Selam Koye Gebresilassie Tadesse Gidey Rtbey Exploring the occurence and risk factors of post-stroke depression among stroke survivors in Africa: a comprehensive systematic review and meta-analysis BMC Public Health Depression Stroke Post-stroke Post-stroke depression Prevalence Incidence and stroke depression |
| title | Exploring the occurence and risk factors of post-stroke depression among stroke survivors in Africa: a comprehensive systematic review and meta-analysis |
| title_full | Exploring the occurence and risk factors of post-stroke depression among stroke survivors in Africa: a comprehensive systematic review and meta-analysis |
| title_fullStr | Exploring the occurence and risk factors of post-stroke depression among stroke survivors in Africa: a comprehensive systematic review and meta-analysis |
| title_full_unstemmed | Exploring the occurence and risk factors of post-stroke depression among stroke survivors in Africa: a comprehensive systematic review and meta-analysis |
| title_short | Exploring the occurence and risk factors of post-stroke depression among stroke survivors in Africa: a comprehensive systematic review and meta-analysis |
| title_sort | exploring the occurence and risk factors of post stroke depression among stroke survivors in africa a comprehensive systematic review and meta analysis |
| topic | Depression Stroke Post-stroke Post-stroke depression Prevalence Incidence and stroke depression |
| url | https://doi.org/10.1186/s12889-025-22685-5 |
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