Use Of A Periodic Vaccination Strategy To Control The Spread Of Epidemics With Seasonally Varying Contact Rate

In this paper, a general periodic vaccination has been applied to control the spread and transmission of an infectious disease with latency. A $SEIRS^1$ epidemic model with general periodic vaccination strategy is analyzed. We suppose that the contact rate has period $T$, and the vaccination functio...

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Main Authors: Islam A. Moneim, David Greenhalgh
Format: Article
Language:English
Published: AIMS Press 2005-07-01
Series:Mathematical Biosciences and Engineering
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Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2005.2.591
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author Islam A. Moneim
David Greenhalgh
author_facet Islam A. Moneim
David Greenhalgh
author_sort Islam A. Moneim
collection DOAJ
description In this paper, a general periodic vaccination has been applied to control the spread and transmission of an infectious disease with latency. A $SEIRS^1$ epidemic model with general periodic vaccination strategy is analyzed. We suppose that the contact rate has period $T$, and the vaccination function has period $LT$, where $L$ is an integer. Also we apply this strategy in a model with seasonal variation in the contact rate. Both the vaccination strategy and the contact rate are general time-dependent periodic functions. The same SEIRS models have been examined for a mixed vaccination strategy composed of both the time-dependent periodic vaccination strategy and the conventional one. A key parameter of the paper is a conjectured value $R^c_0$ for the basic reproduction number. We prove that the disease-free solution (DFS) is globally asymptotically stable (GAS) when $R^{'sup'}_0 1$, then the DFS is unstable, and we prove that there exists a nontrivial periodic solution whose period is the same as that of the vaccination strategy. Some persistence results are also discussed. Necessary and sufficient conditions for the eradication or control of the disease are derived. Threshold conditions for these vaccination strategies to ensure that $R^{'sup'}_0 1$ are also investigated.
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spelling doaj-art-c360237097e044cb9cc74f35d99b3bfd2025-01-24T01:49:00ZengAIMS PressMathematical Biosciences and Engineering1551-00182005-07-012359161110.3934/mbe.2005.2.591Use Of A Periodic Vaccination Strategy To Control The Spread Of Epidemics With Seasonally Varying Contact RateIslam A. Moneim0David Greenhalgh1Department of Mathematics, Faculty of Science, Benha University, BenhaDepartment of Statistics and Modelling Science, Livingstone Tower, 26 Richmond Street, Glasgow G1 1XHIn this paper, a general periodic vaccination has been applied to control the spread and transmission of an infectious disease with latency. A $SEIRS^1$ epidemic model with general periodic vaccination strategy is analyzed. We suppose that the contact rate has period $T$, and the vaccination function has period $LT$, where $L$ is an integer. Also we apply this strategy in a model with seasonal variation in the contact rate. Both the vaccination strategy and the contact rate are general time-dependent periodic functions. The same SEIRS models have been examined for a mixed vaccination strategy composed of both the time-dependent periodic vaccination strategy and the conventional one. A key parameter of the paper is a conjectured value $R^c_0$ for the basic reproduction number. We prove that the disease-free solution (DFS) is globally asymptotically stable (GAS) when $R^{'sup'}_0 1$, then the DFS is unstable, and we prove that there exists a nontrivial periodic solution whose period is the same as that of the vaccination strategy. Some persistence results are also discussed. Necessary and sufficient conditions for the eradication or control of the disease are derived. Threshold conditions for these vaccination strategies to ensure that $R^{'sup'}_0 1$ are also investigated.https://www.aimspress.com/article/doi/10.3934/mbe.2005.2.591disease controlperiodic vaccinationchildhood diseasesbasicreproduction number r0; periodicityuniform strong repellermathematical modellinguniform persis-tence.
spellingShingle Islam A. Moneim
David Greenhalgh
Use Of A Periodic Vaccination Strategy To Control The Spread Of Epidemics With Seasonally Varying Contact Rate
Mathematical Biosciences and Engineering
disease control
periodic vaccination
childhood diseases
basicreproduction number r0; periodicity
uniform strong repeller
mathematical modelling
uniform persis-tence.
title Use Of A Periodic Vaccination Strategy To Control The Spread Of Epidemics With Seasonally Varying Contact Rate
title_full Use Of A Periodic Vaccination Strategy To Control The Spread Of Epidemics With Seasonally Varying Contact Rate
title_fullStr Use Of A Periodic Vaccination Strategy To Control The Spread Of Epidemics With Seasonally Varying Contact Rate
title_full_unstemmed Use Of A Periodic Vaccination Strategy To Control The Spread Of Epidemics With Seasonally Varying Contact Rate
title_short Use Of A Periodic Vaccination Strategy To Control The Spread Of Epidemics With Seasonally Varying Contact Rate
title_sort use of a periodic vaccination strategy to control the spread of epidemics with seasonally varying contact rate
topic disease control
periodic vaccination
childhood diseases
basicreproduction number r0; periodicity
uniform strong repeller
mathematical modelling
uniform persis-tence.
url https://www.aimspress.com/article/doi/10.3934/mbe.2005.2.591
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