Familial Narcolepsy in Dogo Argentino Dogs Is Caused by a Tandem Duplication Mutation in HCRTR2

Familial Narcolepsy in Dogo Argentino Dogs Is Caused by a Tandem Duplication Mutation in HCRTR2

ABSTRACT Background Familial narcolepsy in dogs has been associated with mutations in the HCRTR2 gene in Labrador retrievers, dachshunds, and Doberman pinschers, with the causal mutation differing between breeds. Objective To characterize the genetic mutation responsible for familial narcolepsy in D...

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Bibliographic Details
Main Authors: Alejandra Mondino, Michael W. Vandewege, Rody Artigas, Luis Delucchi, Karen M. Hermida, Camila E. Yanez, Jonah N. Cullen, Steven G. Friedenberg, Kathryn M. Meurs, Joshua A. Stern, Natasha J. Olby
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Journal of Veterinary Internal Medicine
Subjects:
cataplexy
genetic disease
hypocretins
sleep
Online Access:https://doi.org/10.1111/jvim.70056
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