Cloning and sequence analysis of PR-39 gene of porcine antibacterial peptide in bone marrow

Genome RNA was extracted from bone marrow of pig (Duroc × Landrace × Yorkshire) and PR-39 mRNA amplified through PT-PCR with special primers. A DNA fragment about 349 bp in length was obtained. The PCR product was cloned into pGEM-T vector and sequedced. Sequence analysis suggested that this fragmen...

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Bibliographic Details
Main Authors: WANG Yi-zheng, YU Song-dong, LIN Wen-xue
Format: Article
Language:English
Published: Zhejiang University Press 2002-11-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/1008-9209.2002.06.0685
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Summary:Genome RNA was extracted from bone marrow of pig (Duroc × Landrace × Yorkshire) and PR-39 mRNA amplified through PT-PCR with special primers. A DNA fragment about 349 bp in length was obtained. The PCR product was cloned into pGEM-T vector and sequedced. Sequence analysis suggested that this fragment was partial sequence of pr-39 gene cDNA and coded 113 amino acid residues, which constituted the major part of pr-39 mature peptide. The gene fragment gained in this study was consistent with the porcine pr-39 cDNA partial sequence in Genebank.
ISSN:1008-9209
2097-5155