PHARMACOEPIDEMIOLOGIC ANALYSIS OF HOSPITAL TREATMENT OF PATIENTS WITH CEREBRAL INFARCTION AND ATRIAL FIBRILLATION

Aim. To analyze pharmacotherapy of cerebral infarction in patients with atrial fibrillation (AF) in real clinical practice of neurological departments of Saratov hospitals.Material and methods. A retrospective longitudinal pharmacoepidemiologic study was carried out. Medical cards were analyzed in p...

Full description

Saved in:
Bibliographic Details
Main Authors: N. V. Mikheeva, O. V. Reshetko, N. V. Furman
Format: Article
Language:English
Published: Столичная издательская компания 2015-09-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:https://www.rpcardio.online/jour/article/view/291
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849227965638901760
author N. V. Mikheeva
O. V. Reshetko
N. V. Furman
author_facet N. V. Mikheeva
O. V. Reshetko
N. V. Furman
author_sort N. V. Mikheeva
collection DOAJ
description Aim. To analyze pharmacotherapy of cerebral infarction in patients with atrial fibrillation (AF) in real clinical practice of neurological departments of Saratov hospitals.Material and methods. A retrospective longitudinal pharmacoepidemiologic study was carried out. Medical cards were analyzed in patients with cerebral infarction and atrial fibrillation treated in neurology departments from 01.01.2009 to 31.12.2011.Results. Acetylsalicylic acid was prescribed to 66.7% of patients, warfarin – 3.9%. At that target level of international normalised ratio was reached only in 40% of patients. It has been shown frequent (96%) prescriptions of metabolic, neuroprotective and vasoactive drugs with low level of efficacy evidence. Beta-blockers (in 39.3% of patients) and their combination with digoxin (18.7%) were prescribed for heart rate control.Conclusion. Generally, in real clinical practice doctor’s choice of pharmacotherapy of cerebral infarction in patients with AF is not exactly in line with contemporary guidelines. These patients are frequently prescribed drugs with low efficacy and level of evidence.
format Article
id doaj-art-c32c13902e454f7caffc0ebe614a3f4e
institution Kabale University
issn 1819-6446
2225-3653
language English
publishDate 2015-09-01
publisher Столичная издательская компания
record_format Article
series Рациональная фармакотерапия в кардиологии
spelling doaj-art-c32c13902e454f7caffc0ebe614a3f4e2025-08-23T10:00:18ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-09-0110661762410.20996/1819-6446-2014-10-6-617-624291PHARMACOEPIDEMIOLOGIC ANALYSIS OF HOSPITAL TREATMENT OF PATIENTS WITH CEREBRAL INFARCTION AND ATRIAL FIBRILLATIONN. V. Mikheeva0O. V. Reshetko1N. V. Furman2Saratov State Medical University named after V.I. RazumovskySaratov State Medical University named after V.I. RazumovskySaratov Research Institute of CardiologyAim. To analyze pharmacotherapy of cerebral infarction in patients with atrial fibrillation (AF) in real clinical practice of neurological departments of Saratov hospitals.Material and methods. A retrospective longitudinal pharmacoepidemiologic study was carried out. Medical cards were analyzed in patients with cerebral infarction and atrial fibrillation treated in neurology departments from 01.01.2009 to 31.12.2011.Results. Acetylsalicylic acid was prescribed to 66.7% of patients, warfarin – 3.9%. At that target level of international normalised ratio was reached only in 40% of patients. It has been shown frequent (96%) prescriptions of metabolic, neuroprotective and vasoactive drugs with low level of efficacy evidence. Beta-blockers (in 39.3% of patients) and their combination with digoxin (18.7%) were prescribed for heart rate control.Conclusion. Generally, in real clinical practice doctor’s choice of pharmacotherapy of cerebral infarction in patients with AF is not exactly in line with contemporary guidelines. These patients are frequently prescribed drugs with low efficacy and level of evidence.https://www.rpcardio.online/jour/article/view/291cerebral infarctionatrial fibrillationpharmacoepidemiologyantithrombotic agentssecondary prevention
spellingShingle N. V. Mikheeva
O. V. Reshetko
N. V. Furman
PHARMACOEPIDEMIOLOGIC ANALYSIS OF HOSPITAL TREATMENT OF PATIENTS WITH CEREBRAL INFARCTION AND ATRIAL FIBRILLATION
Рациональная фармакотерапия в кардиологии
cerebral infarction
atrial fibrillation
pharmacoepidemiology
antithrombotic agents
secondary prevention
title PHARMACOEPIDEMIOLOGIC ANALYSIS OF HOSPITAL TREATMENT OF PATIENTS WITH CEREBRAL INFARCTION AND ATRIAL FIBRILLATION
title_full PHARMACOEPIDEMIOLOGIC ANALYSIS OF HOSPITAL TREATMENT OF PATIENTS WITH CEREBRAL INFARCTION AND ATRIAL FIBRILLATION
title_fullStr PHARMACOEPIDEMIOLOGIC ANALYSIS OF HOSPITAL TREATMENT OF PATIENTS WITH CEREBRAL INFARCTION AND ATRIAL FIBRILLATION
title_full_unstemmed PHARMACOEPIDEMIOLOGIC ANALYSIS OF HOSPITAL TREATMENT OF PATIENTS WITH CEREBRAL INFARCTION AND ATRIAL FIBRILLATION
title_short PHARMACOEPIDEMIOLOGIC ANALYSIS OF HOSPITAL TREATMENT OF PATIENTS WITH CEREBRAL INFARCTION AND ATRIAL FIBRILLATION
title_sort pharmacoepidemiologic analysis of hospital treatment of patients with cerebral infarction and atrial fibrillation
topic cerebral infarction
atrial fibrillation
pharmacoepidemiology
antithrombotic agents
secondary prevention
url https://www.rpcardio.online/jour/article/view/291
work_keys_str_mv AT nvmikheeva pharmacoepidemiologicanalysisofhospitaltreatmentofpatientswithcerebralinfarctionandatrialfibrillation
AT ovreshetko pharmacoepidemiologicanalysisofhospitaltreatmentofpatientswithcerebralinfarctionandatrialfibrillation
AT nvfurman pharmacoepidemiologicanalysisofhospitaltreatmentofpatientswithcerebralinfarctionandatrialfibrillation