Determining the mechanism of Shuxuening injection against liver cirrhosis through network pharmacology and animal experiments

Determining the mechanism of Shuxuening injection against liver cirrhosis through network pharmacology and animal experiments

Objective: To screen and identify the key active molecules, signaling pathways, and therapeutic targets of Shuxuening (SXN) injection for treating liver cirrhosis (LC) and to evaluate its therapeutic potential using a mouse model. Methods: Target genes of SXN and LC were retrieved from public databa...

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Bibliographic Details
Main Authors: Qiyao Liu, Tingyu Zhang, Yongan Ye, Xin Sun, Huan Xia, Xu Cao, Xiaoke Li, Wenying Qi, Yue Chen, Xiaobin Zao
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Traditional Chinese Medical Sciences
Subjects:
Shuxuening injection
Ginkgo biloba extract
Liver cirrhosis
Network pharmacology
Animal experiments
Online Access:http://www.sciencedirect.com/science/article/pii/S2095754824001030
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