Lung cancer screening: Is there a future?

Lung cancer is the leading cause of cancer death worldwide with an average rate of 40-100/100,000 depending on the level of deprivation, and the rates are higher in smokers. The National Lung Screening Trial using three consecutive annual low-dose computed tomography scans is the first and largest s...

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Main Author: Mary ER O′Brien
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2014-01-01
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
Online Access:http://www.ijmpo.org/article.asp?issn=0971-5851;year=2014;volume=35;issue=4;spage=249;epage=252;aulast=O'Brien
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author Mary ER O′Brien
author_facet Mary ER O′Brien
author_sort Mary ER O′Brien
collection DOAJ
description Lung cancer is the leading cause of cancer death worldwide with an average rate of 40-100/100,000 depending on the level of deprivation, and the rates are higher in smokers. The National Lung Screening Trial using three consecutive annual low-dose computed tomography scans is the first and largest screening study to show clear evidence of a significant reduction in lung cancer mortality in selected high-risk subjects. The many on-going European screening studies will generate information on the groups of subjects that may or may not benefit from screening (demographics, pack-years smoked, length of smoking, number of years from quitting etc.) and the required frequency and duration of the intervention. Smoking cessation remains the most important tool for general improvement in health outcomes and in particular lung cancer prevention. Early intervention for investigations of symptoms that are considered mild or common could also change the outcome. Doctors and patients must become increasingly aware that these common symptoms are also potentially symptoms of lung cancer and are not ′normal′ even in smokers.
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spelling doaj-art-c2f3ad2c7e1c4e2cb93bc04f054b6f322025-08-20T02:02:29ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58512014-01-0135424925210.4103/0971-5851.144984Lung cancer screening: Is there a future?Mary ER O′BrienLung cancer is the leading cause of cancer death worldwide with an average rate of 40-100/100,000 depending on the level of deprivation, and the rates are higher in smokers. The National Lung Screening Trial using three consecutive annual low-dose computed tomography scans is the first and largest screening study to show clear evidence of a significant reduction in lung cancer mortality in selected high-risk subjects. The many on-going European screening studies will generate information on the groups of subjects that may or may not benefit from screening (demographics, pack-years smoked, length of smoking, number of years from quitting etc.) and the required frequency and duration of the intervention. Smoking cessation remains the most important tool for general improvement in health outcomes and in particular lung cancer prevention. Early intervention for investigations of symptoms that are considered mild or common could also change the outcome. Doctors and patients must become increasingly aware that these common symptoms are also potentially symptoms of lung cancer and are not ′normal′ even in smokers.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2014;volume=35;issue=4;spage=249;epage=252;aulast=O'BrienLung cancerlow dose computed tomography scanscreening
spellingShingle Mary ER O′Brien
Lung cancer screening: Is there a future?
Indian Journal of Medical and Paediatric Oncology
Lung cancer
low dose computed tomography scan
screening
title Lung cancer screening: Is there a future?
title_full Lung cancer screening: Is there a future?
title_fullStr Lung cancer screening: Is there a future?
title_full_unstemmed Lung cancer screening: Is there a future?
title_short Lung cancer screening: Is there a future?
title_sort lung cancer screening is there a future
topic Lung cancer
low dose computed tomography scan
screening
url http://www.ijmpo.org/article.asp?issn=0971-5851;year=2014;volume=35;issue=4;spage=249;epage=252;aulast=O'Brien
work_keys_str_mv AT maryerobrien lungcancerscreeningisthereafuture