Systematic review of amyloid-beta clearance proteins from the brain to the periphery: implications for Alzheimer’s disease diagnosis and therapeutic targets

Systematic review of amyloid-beta clearance proteins from the brain to the periphery: implications for Alzheimer’s disease diagnosis and therapeutic targets

Amyloid-beta clearance plays a key role in the pathogenesis of Alzheimer’s disease. However, the variation in functional proteins involved in amyloid-beta clearance and their correlation with amyloid-beta levels remain unclear. In this study, we conducted meta-analyses and a systematic review using...

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Bibliographic Details
Main Authors: Letian Huang, Mingyue Liu, Ze Li, Bing Li, Jiahe Wang, Ke Zhang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-12-01
Series:Neural Regeneration Research
Subjects:
alzheimer’s disease
amyloid-β
blood‒brain barrier
cerebrospinal fluid
diagnostic biomarker
meta-analysis
mild cognitive impairment
peripheral blood
systematic review
therapeutic targets
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-24-00865
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