Melatonin: biological significance and therapeutic properties
Melatonin is a hormone secreted by the pineal gland that is important for various neurological and endocrine processes in the body. With age and various diseases, a decrease in the concentration of melatonin is observed, its antioxidant effect is reduced, therefore, the circadian rhythm is disturbe...
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| Format: | Article |
| Language: | English |
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Vilnius University Press
2022-09-01
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| Series: | Neurologijos seminarai |
| Subjects: | |
| Online Access: | https://www.journals.vu.lt/neurologijos_seminarai/article/view/33254 |
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| _version_ | 1832593122954051584 |
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| author | V. Rimšaitė K. Bogdanavičienė G. Gudavičiūtė E. Pajėdienė |
| author_facet | V. Rimšaitė K. Bogdanavičienė G. Gudavičiūtė E. Pajėdienė |
| author_sort | V. Rimšaitė |
| collection | DOAJ |
| description |
Melatonin is a hormone secreted by the pineal gland that is important for various neurological and endocrine processes in the body. With age and various diseases, a decrease in the concentration of melatonin is observed, its antioxidant effect is reduced, therefore, the circadian rhythm is disturbed, mental disorders occur, and the risk of oncological, neurodegenerative and cardiovascular diseases increases. Due to its wide spectrum of action, melatonin can be used successfully and safely for the prevention and treatment of various diseases. In recent years, the antineoplastic, anti-inflammatory, and analgesic effects of melatonin have been increasingly investigated, as has the potential positive effects of melatonin on adjuvant therapy for COVID-19 infection. By adapting the natural properties of melatonin for therapeutic purposes, exogenous melatonin preparations can potentially be used in addition to, or even as a substitute for, other currently used drugs. However, it is important to weigh the benefits and the risks. Although current studies show relative safety with low doses of exogenous melatonin, it is necessary to further investigate and analyze the safety and efficacy of these agents in the short and long term.
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| format | Article |
| id | doaj-art-c2e00dc994e74880adedd5bc83f90fd2 |
| institution | Kabale University |
| issn | 1392-3064 2424-5917 |
| language | English |
| publishDate | 2022-09-01 |
| publisher | Vilnius University Press |
| record_format | Article |
| series | Neurologijos seminarai |
| spelling | doaj-art-c2e00dc994e74880adedd5bc83f90fd22025-01-20T18:22:14ZengVilnius University PressNeurologijos seminarai1392-30642424-59172022-09-01262 (92)10.29014/NS.2022.26.7Melatonin: biological significance and therapeutic propertiesV. Rimšaitė0K. Bogdanavičienė1G. Gudavičiūtė2E. Pajėdienė3Lithuanian University of Health SciencesLithuanian University of Health SciencesLithuanian University of Health SciencesLithuanian University of Health Sciences Melatonin is a hormone secreted by the pineal gland that is important for various neurological and endocrine processes in the body. With age and various diseases, a decrease in the concentration of melatonin is observed, its antioxidant effect is reduced, therefore, the circadian rhythm is disturbed, mental disorders occur, and the risk of oncological, neurodegenerative and cardiovascular diseases increases. Due to its wide spectrum of action, melatonin can be used successfully and safely for the prevention and treatment of various diseases. In recent years, the antineoplastic, anti-inflammatory, and analgesic effects of melatonin have been increasingly investigated, as has the potential positive effects of melatonin on adjuvant therapy for COVID-19 infection. By adapting the natural properties of melatonin for therapeutic purposes, exogenous melatonin preparations can potentially be used in addition to, or even as a substitute for, other currently used drugs. However, it is important to weigh the benefits and the risks. Although current studies show relative safety with low doses of exogenous melatonin, it is necessary to further investigate and analyze the safety and efficacy of these agents in the short and long term. https://www.journals.vu.lt/neurologijos_seminarai/article/view/33254melatoninmelatonin functionmelatonin and agingmelatonin treatmentcircadian rhythmrhythm of sleep and alertness |
| spellingShingle | V. Rimšaitė K. Bogdanavičienė G. Gudavičiūtė E. Pajėdienė Melatonin: biological significance and therapeutic properties Neurologijos seminarai melatonin melatonin function melatonin and aging melatonin treatment circadian rhythm rhythm of sleep and alertness |
| title | Melatonin: biological significance and therapeutic properties |
| title_full | Melatonin: biological significance and therapeutic properties |
| title_fullStr | Melatonin: biological significance and therapeutic properties |
| title_full_unstemmed | Melatonin: biological significance and therapeutic properties |
| title_short | Melatonin: biological significance and therapeutic properties |
| title_sort | melatonin biological significance and therapeutic properties |
| topic | melatonin melatonin function melatonin and aging melatonin treatment circadian rhythm rhythm of sleep and alertness |
| url | https://www.journals.vu.lt/neurologijos_seminarai/article/view/33254 |
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