Clinical Challenges in Regenerative Endodontic Therapy: A Review

Regenerative endodontic therapy RET has drawn a great deal of interest and is widely recognized because it preserves the function and endurance of teeth. Although it is routinely performed on immature teeth with periapical disease the treatment outcomes remain unpredictable. Ins...

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Bibliographic Details
Main Author: Vivek Thakur
Format: Article
Language:English
Published: Rajiv Gandhi University of Health Sciences 2025-01-01
Series:RGUHS Journal of Dental Sciences
Online Access:https://journalgrid.com/view/article/rjds/12434341
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Summary:Regenerative endodontic therapy RET has drawn a great deal of interest and is widely recognized because it preserves the function and endurance of teeth. Although it is routinely performed on immature teeth with periapical disease the treatment outcomes remain unpredictable. Instead of producing fibrous connective tissue and amorphous mineral deposits pulp-dentin regeneration should be the real benchmark of RET. Still we have not yet achieved the benchmark of full innervation and vascularization of the generated tissue in the root canal. The main challenges faced with the current clinical protocol of RET are the complete disinfection of root canal space and enhancing pulplike tissue regeneration. This article will address the key challenges and strategies that focus on realizing the goal of regenerative endodontic therapy.
ISSN:0976-9439