Integration of a specialist pharmacist-led multidisciplinary team in primary care: preventing strokes in people with atrial fibrillation across North East London

Public Health England outlines a national ambition of anticoagulating 90% of eligible patients with atrial fibrillation (AF) by 2029. In 2019/2020, two out of three boroughs reviewed in this study were in the bottom 10% of boroughs compared with others within England. Stroke National Audit data for...

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Main Authors: Riyaz Patel, Sotiris Antoniou, Shabana Ali, Mital Patel, Matt Kearney, Jagjot Kaur Chahal, John Robson, Paul Wright, Afzal Sohaib, Richard Clements, Angela Theodoulou
Format: Article
Language:English
Published: BMJ Publishing Group 2025-01-01
Series:BMJ Open Quality
Online Access:https://bmjopenquality.bmj.com/content/14/1/e002804.full
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author Riyaz Patel
Sotiris Antoniou
Shabana Ali
Mital Patel
Matt Kearney
Jagjot Kaur Chahal
John Robson
Paul Wright
Afzal Sohaib
Richard Clements
Angela Theodoulou
author_facet Riyaz Patel
Sotiris Antoniou
Shabana Ali
Mital Patel
Matt Kearney
Jagjot Kaur Chahal
John Robson
Paul Wright
Afzal Sohaib
Richard Clements
Angela Theodoulou
author_sort Riyaz Patel
collection DOAJ
description Public Health England outlines a national ambition of anticoagulating 90% of eligible patients with atrial fibrillation (AF) by 2029. In 2019/2020, two out of three boroughs reviewed in this study were in the bottom 10% of boroughs compared with others within England. Stroke National Audit data for these three boroughs from 2019 to 2020 identified that in patients with known AF admitted to hospital with strokes, 37% were not anticoagulated. Evidence shows that one stroke can be prevented for every 25 patients with AF treated with anticoagulation, reducing the burden of stroke and stroke-related disabilities.In 2020, hospital specialist cardiovascular pharmacists were commissioned to identify patients with AF at high ischaemic risk (CHA2DS2VASc≥2) in three boroughs by working with general practitioners (GPs) and practice-based pharmacists. Using digital ‘proactive care frameworks’ created by UCLPartners and the Clinical Effectiveness Group, Queen Mary University of London, baseline searches of GP records enabled clinical teams to risk stratify and prioritise patients with AF for review. Patients not on anticoagulation were categorised as high risk and were reviewed for initiation of anticoagulation. The second priority was patients on dual antithrombotic therapy to determine if antiplatelet therapy could be stopped to minimise bleeding risk.At baseline (March 2020), nationally available data (extracted from CVDPREVENT) showed that 81% of patients with AF at high ischaemic risk across the three selected boroughs were anticoagulated. Repeated data extraction in March 2023, showed 94% of patients with AF at high ischaemic risk were anticoagulated, an absolute improvement of 13%, with 415 patients initiated on anticoagulant therapy over 3 years, translating to 17 strokes prevented. There was a 52% reduction in dual antithrombotic therapy, preventing an estimated three major bleeds.Improvements were achieved through a combination of specialist pharmacist reviews, GP and practice-based pharmacist training and virtual multidisciplinary reviews supporting the integration of specialists into a primary care setting to enable joined-up pathways for effective stroke prevention.
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spelling doaj-art-c2c657132604428d8da050b9833562d52025-02-03T18:50:10ZengBMJ Publishing GroupBMJ Open Quality2399-66412025-01-0114110.1136/bmjoq-2024-002804Integration of a specialist pharmacist-led multidisciplinary team in primary care: preventing strokes in people with atrial fibrillation across North East LondonRiyaz Patel0Sotiris Antoniou1Shabana Ali2Mital Patel3Matt Kearney4Jagjot Kaur Chahal5John Robson6Paul Wright7Afzal Sohaib8Richard Clements9Angela Theodoulou10Department of Cardiology, Barts Health NHS Trust, London, UKDepartment of Pharmacy, Barts Health NHS Trust, London, UKNHS Redbridge Place, London, UKDepartment of Pharmacy, Barts Health NHS Trust, London, UKUCLPartners, London, UKDepartment of Pharmacy, Barts Health NHS Trust, London, UKClinical Effectiveness Group, Queen Mary University of London, London, UK2University of Virginia, Charlottesville, VA, USADepartment of Cardiology, Barts Health NHS Trust, London, UKNorth East London Integrated Care Board, London, UKDepartment of Haematology, Barts Health NHS Trust, London, UKPublic Health England outlines a national ambition of anticoagulating 90% of eligible patients with atrial fibrillation (AF) by 2029. In 2019/2020, two out of three boroughs reviewed in this study were in the bottom 10% of boroughs compared with others within England. Stroke National Audit data for these three boroughs from 2019 to 2020 identified that in patients with known AF admitted to hospital with strokes, 37% were not anticoagulated. Evidence shows that one stroke can be prevented for every 25 patients with AF treated with anticoagulation, reducing the burden of stroke and stroke-related disabilities.In 2020, hospital specialist cardiovascular pharmacists were commissioned to identify patients with AF at high ischaemic risk (CHA2DS2VASc≥2) in three boroughs by working with general practitioners (GPs) and practice-based pharmacists. Using digital ‘proactive care frameworks’ created by UCLPartners and the Clinical Effectiveness Group, Queen Mary University of London, baseline searches of GP records enabled clinical teams to risk stratify and prioritise patients with AF for review. Patients not on anticoagulation were categorised as high risk and were reviewed for initiation of anticoagulation. The second priority was patients on dual antithrombotic therapy to determine if antiplatelet therapy could be stopped to minimise bleeding risk.At baseline (March 2020), nationally available data (extracted from CVDPREVENT) showed that 81% of patients with AF at high ischaemic risk across the three selected boroughs were anticoagulated. Repeated data extraction in March 2023, showed 94% of patients with AF at high ischaemic risk were anticoagulated, an absolute improvement of 13%, with 415 patients initiated on anticoagulant therapy over 3 years, translating to 17 strokes prevented. There was a 52% reduction in dual antithrombotic therapy, preventing an estimated three major bleeds.Improvements were achieved through a combination of specialist pharmacist reviews, GP and practice-based pharmacist training and virtual multidisciplinary reviews supporting the integration of specialists into a primary care setting to enable joined-up pathways for effective stroke prevention.https://bmjopenquality.bmj.com/content/14/1/e002804.full
spellingShingle Riyaz Patel
Sotiris Antoniou
Shabana Ali
Mital Patel
Matt Kearney
Jagjot Kaur Chahal
John Robson
Paul Wright
Afzal Sohaib
Richard Clements
Angela Theodoulou
Integration of a specialist pharmacist-led multidisciplinary team in primary care: preventing strokes in people with atrial fibrillation across North East London
BMJ Open Quality
title Integration of a specialist pharmacist-led multidisciplinary team in primary care: preventing strokes in people with atrial fibrillation across North East London
title_full Integration of a specialist pharmacist-led multidisciplinary team in primary care: preventing strokes in people with atrial fibrillation across North East London
title_fullStr Integration of a specialist pharmacist-led multidisciplinary team in primary care: preventing strokes in people with atrial fibrillation across North East London
title_full_unstemmed Integration of a specialist pharmacist-led multidisciplinary team in primary care: preventing strokes in people with atrial fibrillation across North East London
title_short Integration of a specialist pharmacist-led multidisciplinary team in primary care: preventing strokes in people with atrial fibrillation across North East London
title_sort integration of a specialist pharmacist led multidisciplinary team in primary care preventing strokes in people with atrial fibrillation across north east london
url https://bmjopenquality.bmj.com/content/14/1/e002804.full
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