Navigational Bronchoscopy with Cryobiopsy for Diagnosis of ILD

Background. Interstitial lung diseases (ILDs) are a group of parenchymal pulmonary diseases in which pathologic diagnosis is essential. Although cryobiopsy has a high diagnostic yield, the complication rate remains high. Case Presentation. We report two cases of lung cryobiopsy guided by navigationa...

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Main Authors: Fernando Figueroa Rodriguez, Asfar Ghauri, Tony Abdo, Salim Daouk, Shideler Barbara, Houssein A. Youness
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Pulmonology
Online Access:http://dx.doi.org/10.1155/2022/5128432
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author Fernando Figueroa Rodriguez
Asfar Ghauri
Tony Abdo
Salim Daouk
Shideler Barbara
Houssein A. Youness
author_facet Fernando Figueroa Rodriguez
Asfar Ghauri
Tony Abdo
Salim Daouk
Shideler Barbara
Houssein A. Youness
author_sort Fernando Figueroa Rodriguez
collection DOAJ
description Background. Interstitial lung diseases (ILDs) are a group of parenchymal pulmonary diseases in which pathologic diagnosis is essential. Although cryobiopsy has a high diagnostic yield, the complication rate remains high. Case Presentation. We report two cases of lung cryobiopsy guided by navigational bronchoscopy (LCB) for the diagnosis of ILD. In both cases, a CT chest angiogram (CTA) using a navigational protocol was performed. Targets were premarked and reached with the navigational system. Radial ultrasound (RU) was applied in combination with fluoroscopy guidance (FG) prior to sampling. Both patients achieved a final diagnosis; they were discharged home after procedure and no complications were noted. Discussion. By using a CTA with navigational guidance, we were able to perform cryobiopsy in areas with most disease activity and least vascularization. Conclusion. LCB used with navigational guidance for the diagnosis of ILD provides may be a safe and effective procedure that provides high diagnostic yield. Limitations include cost, availability, and expertise. Larger trials are needed to confirm the additional benefit.
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series Case Reports in Pulmonology
spelling doaj-art-c2c1a1af670448c4aab3452fbf26b9ad2025-02-03T01:19:58ZengWileyCase Reports in Pulmonology2090-68542022-01-01202210.1155/2022/5128432Navigational Bronchoscopy with Cryobiopsy for Diagnosis of ILDFernando Figueroa Rodriguez0Asfar Ghauri1Tony Abdo2Salim Daouk3Shideler Barbara4Houssein A. Youness5Interventional Pulmonary ProgramInterventional Pulmonary ProgramInterventional Pulmonary ProgramInterventional Pulmonary ProgramInterventional Pulmonary ProgramInterventional Pulmonary ProgramBackground. Interstitial lung diseases (ILDs) are a group of parenchymal pulmonary diseases in which pathologic diagnosis is essential. Although cryobiopsy has a high diagnostic yield, the complication rate remains high. Case Presentation. We report two cases of lung cryobiopsy guided by navigational bronchoscopy (LCB) for the diagnosis of ILD. In both cases, a CT chest angiogram (CTA) using a navigational protocol was performed. Targets were premarked and reached with the navigational system. Radial ultrasound (RU) was applied in combination with fluoroscopy guidance (FG) prior to sampling. Both patients achieved a final diagnosis; they were discharged home after procedure and no complications were noted. Discussion. By using a CTA with navigational guidance, we were able to perform cryobiopsy in areas with most disease activity and least vascularization. Conclusion. LCB used with navigational guidance for the diagnosis of ILD provides may be a safe and effective procedure that provides high diagnostic yield. Limitations include cost, availability, and expertise. Larger trials are needed to confirm the additional benefit.http://dx.doi.org/10.1155/2022/5128432
spellingShingle Fernando Figueroa Rodriguez
Asfar Ghauri
Tony Abdo
Salim Daouk
Shideler Barbara
Houssein A. Youness
Navigational Bronchoscopy with Cryobiopsy for Diagnosis of ILD
Case Reports in Pulmonology
title Navigational Bronchoscopy with Cryobiopsy for Diagnosis of ILD
title_full Navigational Bronchoscopy with Cryobiopsy for Diagnosis of ILD
title_fullStr Navigational Bronchoscopy with Cryobiopsy for Diagnosis of ILD
title_full_unstemmed Navigational Bronchoscopy with Cryobiopsy for Diagnosis of ILD
title_short Navigational Bronchoscopy with Cryobiopsy for Diagnosis of ILD
title_sort navigational bronchoscopy with cryobiopsy for diagnosis of ild
url http://dx.doi.org/10.1155/2022/5128432
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