Exploring the potential mediating role of systemic antibiotics in the association between early-life lower respiratory tract infections and asthma at age 5 in the CHILD study

Exploring the potential mediating role of systemic antibiotics in the association between early-life lower respiratory tract infections and asthma at age 5 in the CHILD study

ObjectiveLower respiratory tract infections (LRTIs) in early life are one of the strongest risk factors for childhood asthma and are often treated with systemic antibiotics (IV or oral). We aimed to explore the association between early-life LRTIs and systemic antibiotics on asthma development and t...

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Main Authors: Maria V. Medeleanu, Myrtha E. Reyna, Darlene L. Y. Dai, Geoffrey L. Winsor, Fiona S. L. Brinkman, Rahul Verma, Ella Nugent, Nashita Riaz, Elinor Simons, Piushkumar J. Mandhane, Meghan B. Azad, Stuart E. Turvey, Theo J. Moraes, Padmaja Subbarao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Allergy
Subjects:
preschool asthma
respiratory tract infections
antibiotics
mediation analyses
cohort study
clinical epidemiology
Online Access:https://www.frontiersin.org/articles/10.3389/falgy.2024.1463867/full
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https://www.frontiersin.org/articles/10.3389/falgy.2024.1463867/full

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