A strategy to increase identification of patients with Familial Hypercholesterolemia: Application of the Simon Broome lipid criteria in a large-scale retrospective analysis

A strategy to increase identification of patients with Familial Hypercholesterolemia: Application of the Simon Broome lipid criteria in a large-scale retrospective analysis

Introduction: Familial Hypercholesterolemia (FH) is a primarily autosomal dominant condition characterized by markedly elevated low-density lipoprotein-cholesterol (LDL-c) and an increased risk of atherosclerosis and cardiovascular disease (CVD). Though early identification and treatment are crucial...

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Bibliographic Details
Main Authors: James K. Fleming, Renee M. Sullivan, David Alfego, Natalia T. Leach, Tamara J. Richman, Jill Rafalko
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:American Journal of Preventive Cardiology
Subjects:
Hypercholesterolemia
Cholesterol
Low density lipoproteins
Genetic testing
Algorithms
Cardiovascular risk factors
Online Access:http://www.sciencedirect.com/science/article/pii/S2666667725000030
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