Successful Management of Refractory Heart Failure and Multi-Organ Dysfunction in a Patient with CRT-D and Acute Pulmonary Edema: A Case Report

Introduction: Heart failure with reduced ejection fraction (HFrEF) is a progressive condition often complicated by acute decompensations that require advanced medical interventions. Cardiac resynchronization therapy with a defibrillator (CRT-D) has significantly improved outcomes in patients with se...

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Main Authors: Marsela Goga, Saimir Kuci, Alfred Ibrahimi, Ermal Likaj, Alvi Cela, Romina Teliti, Ormir Shurdha, Erilda Selimi, Jacob Zeitani
Format: Article
Language:English
Published: Albanian Society for Trauma and Emergency Surgery 2025-01-01
Series:Albanian Journal of Trauma and Emergency Surgery
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Online Access:http://journal.astes.org.al/AJTES/index.php/AJTES/article/view/442
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author Marsela Goga
Saimir Kuci
Alfred Ibrahimi
Ermal Likaj
Alvi Cela
Romina Teliti
Ormir Shurdha
Erilda Selimi
Jacob Zeitani
author_facet Marsela Goga
Saimir Kuci
Alfred Ibrahimi
Ermal Likaj
Alvi Cela
Romina Teliti
Ormir Shurdha
Erilda Selimi
Jacob Zeitani
author_sort Marsela Goga
collection DOAJ
description Introduction: Heart failure with reduced ejection fraction (HFrEF) is a progressive condition often complicated by acute decompensations that require advanced medical interventions. Cardiac resynchronization therapy with a defibrillator (CRT-D) has significantly improved outcomes in patients with severe heart failure. However, challenges persist when faced with acute events such as pulmonary edema, pneumonia, and multi-organ dysfunction syndrome. Multidisciplinary, intensive care unit (ICU)-based management is critical for these complex cases. This case report presents the successful management of a 61-year-old female patient with a history of severe HFrEF and implanted CRT-D. Despite severe hypoxemia, hypotension, and metabolic acidosis, a multidisciplinary approach—including mechanical ventilation, intra-aortic balloon pump (IABP), continuous renal replacement therapy (CRRT), and transfusion—enabled recovery. The patient was admitted to the ICU with acute pulmonary edema, pneumonia, and multi-organ dysfunction syndrome, characterized by severe hypoxemia, hypotension, and metabolic acidosis. Over three weeks, the patient regained hemodynamic stability, renal function, and respiratory independence. This case demonstrates the potential for recovery in patients with severe heart failure complicated by acute pulmonary edema and multi-organ dysfunction when treated with an integrated, multidisciplinary approach. Conclusion: Advanced critical care strategies, including mechanical ventilation, intra-aortic balloon pump support, and continuous renal replacement therapy, were essential in stabilizing the patient. The outcome underscores the value of personalized, team-based critical care in managing life-threatening complications in heart failure patients with CRT-D.
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record_format Article
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spelling doaj-art-c275aa46c96f4c15aa3240f66f9d03222025-01-19T14:24:38ZengAlbanian Society for Trauma and Emergency SurgeryAlbanian Journal of Trauma and Emergency Surgery2521-87782616-49222025-01-019110.32391/ajtes.v9i1.442Successful Management of Refractory Heart Failure and Multi-Organ Dysfunction in a Patient with CRT-D and Acute Pulmonary Edema: A Case ReportMarsela Goga0Saimir Kuci1Alfred Ibrahimi2Ermal Likaj3Alvi Cela4Romina Teliti5Ormir Shurdha6Erilda Selimi7Jacob Zeitani8Anesthesia & ICU Service, German Hospital International, Tirana, ALBANIAAnesthesia & ICU Service, German Hospital International, Tirana, ALBANIAAnesthesia & ICU Service, German Hospital International, Tirana, ALBANIACardiac Surgery Service, German Hospital International, Tirana, ALBANIAAnesthesia & ICU Service, German Hospital International, Tirana, ALBANIACardiology Service, German Hospital International, Tirana, ALBANIACardiology Service, German Hospital International, Tirana, ALBANIACardiology Service, German Hospital International, Tirana, ALBANIACardiac Surgery Service, German Hospital International, Tirana, ALBANIAIntroduction: Heart failure with reduced ejection fraction (HFrEF) is a progressive condition often complicated by acute decompensations that require advanced medical interventions. Cardiac resynchronization therapy with a defibrillator (CRT-D) has significantly improved outcomes in patients with severe heart failure. However, challenges persist when faced with acute events such as pulmonary edema, pneumonia, and multi-organ dysfunction syndrome. Multidisciplinary, intensive care unit (ICU)-based management is critical for these complex cases. This case report presents the successful management of a 61-year-old female patient with a history of severe HFrEF and implanted CRT-D. Despite severe hypoxemia, hypotension, and metabolic acidosis, a multidisciplinary approach—including mechanical ventilation, intra-aortic balloon pump (IABP), continuous renal replacement therapy (CRRT), and transfusion—enabled recovery. The patient was admitted to the ICU with acute pulmonary edema, pneumonia, and multi-organ dysfunction syndrome, characterized by severe hypoxemia, hypotension, and metabolic acidosis. Over three weeks, the patient regained hemodynamic stability, renal function, and respiratory independence. This case demonstrates the potential for recovery in patients with severe heart failure complicated by acute pulmonary edema and multi-organ dysfunction when treated with an integrated, multidisciplinary approach. Conclusion: Advanced critical care strategies, including mechanical ventilation, intra-aortic balloon pump support, and continuous renal replacement therapy, were essential in stabilizing the patient. The outcome underscores the value of personalized, team-based critical care in managing life-threatening complications in heart failure patients with CRT-D. http://journal.astes.org.al/AJTES/index.php/AJTES/article/view/442Heart failureHFrEFCRT-DAPEMODIABP
spellingShingle Marsela Goga
Saimir Kuci
Alfred Ibrahimi
Ermal Likaj
Alvi Cela
Romina Teliti
Ormir Shurdha
Erilda Selimi
Jacob Zeitani
Successful Management of Refractory Heart Failure and Multi-Organ Dysfunction in a Patient with CRT-D and Acute Pulmonary Edema: A Case Report
Albanian Journal of Trauma and Emergency Surgery
Heart failure
HFrEF
CRT-D
APE
MOD
IABP
title Successful Management of Refractory Heart Failure and Multi-Organ Dysfunction in a Patient with CRT-D and Acute Pulmonary Edema: A Case Report
title_full Successful Management of Refractory Heart Failure and Multi-Organ Dysfunction in a Patient with CRT-D and Acute Pulmonary Edema: A Case Report
title_fullStr Successful Management of Refractory Heart Failure and Multi-Organ Dysfunction in a Patient with CRT-D and Acute Pulmonary Edema: A Case Report
title_full_unstemmed Successful Management of Refractory Heart Failure and Multi-Organ Dysfunction in a Patient with CRT-D and Acute Pulmonary Edema: A Case Report
title_short Successful Management of Refractory Heart Failure and Multi-Organ Dysfunction in a Patient with CRT-D and Acute Pulmonary Edema: A Case Report
title_sort successful management of refractory heart failure and multi organ dysfunction in a patient with crt d and acute pulmonary edema a case report
topic Heart failure
HFrEF
CRT-D
APE
MOD
IABP
url http://journal.astes.org.al/AJTES/index.php/AJTES/article/view/442
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