Ureteroscopic Laser Treatment of Upper Urinary Tract Urothelial Cell Carcinomas: Can a Tumour Free Status Be Achieved?
Introduction. In cases of anatomic or functional single kidney with urothelial tumours of the upper urinary tract, the endoscopic laser ablation has proven efficacious. Based on the knowledge that low-grade, low-stage upper tract transitional cell carcinomas rarely progress to invasive lesions, indi...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Advances in Urology |
| Online Access: | http://dx.doi.org/10.1155/2013/429585 |
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| author | Christos Kalaitzis Athanasios Zisimopoulos Stilianos Giannakopoulos Stavros Touloupidis |
| author_facet | Christos Kalaitzis Athanasios Zisimopoulos Stilianos Giannakopoulos Stavros Touloupidis |
| author_sort | Christos Kalaitzis |
| collection | DOAJ |
| description | Introduction. In cases of anatomic or functional single kidney with urothelial tumours of the upper urinary tract, the endoscopic laser ablation has proven efficacious. Based on the knowledge that low-grade, low-stage upper tract transitional cell carcinomas rarely progress to invasive lesions, indications for endoscopic laser ablation have expanded to include patients with bilateral functioning kidneys and low-grade tumours. The question that remains to be answered is whether endoscopic laser ablation has the ability to completely eradicate upper urinary tract tumours. Methods. We performed in 25 patients in a period of 11 years 288 ureteroscopies and, if needed, laser ablation of upper urinary tract tumours in imperative indication. Results. In 32% of the patients the cancer remained even after several laser sessions. 64% of patients were tumour free after one or more laser sessions but remained clear only for the next 3 months. Only 1 patient was tumour free for a period of 68 months after 1 session of laser treatment. The procedure had low complication rates. Conclusion. The laser technology and the introduction of small diameter semirigid and flexible ureteroscopes made ablation of upper urinary tract tumours possible and safe. Nevertheless a complete resection of the carcinomas is rarely possible. |
| format | Article |
| id | doaj-art-c264df143dd141f6a9c595fd5ce2db61 |
| institution | Kabale University |
| issn | 1687-6369 1687-6377 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Urology |
| spelling | doaj-art-c264df143dd141f6a9c595fd5ce2db612025-02-03T01:02:19ZengWileyAdvances in Urology1687-63691687-63772013-01-01201310.1155/2013/429585429585Ureteroscopic Laser Treatment of Upper Urinary Tract Urothelial Cell Carcinomas: Can a Tumour Free Status Be Achieved?Christos Kalaitzis0Athanasios Zisimopoulos1Stilianos Giannakopoulos2Stavros Touloupidis3Department of Urology, University of Thrace, 68100 Alexandroupolis, GreeceDepartment of Nuclear Medicine, University of Thrace, 68100 Alexandroupolis, GreeceDepartment of Urology, University of Thrace, 68100 Alexandroupolis, GreeceDepartment of Urology, University of Thrace, 68100 Alexandroupolis, GreeceIntroduction. In cases of anatomic or functional single kidney with urothelial tumours of the upper urinary tract, the endoscopic laser ablation has proven efficacious. Based on the knowledge that low-grade, low-stage upper tract transitional cell carcinomas rarely progress to invasive lesions, indications for endoscopic laser ablation have expanded to include patients with bilateral functioning kidneys and low-grade tumours. The question that remains to be answered is whether endoscopic laser ablation has the ability to completely eradicate upper urinary tract tumours. Methods. We performed in 25 patients in a period of 11 years 288 ureteroscopies and, if needed, laser ablation of upper urinary tract tumours in imperative indication. Results. In 32% of the patients the cancer remained even after several laser sessions. 64% of patients were tumour free after one or more laser sessions but remained clear only for the next 3 months. Only 1 patient was tumour free for a period of 68 months after 1 session of laser treatment. The procedure had low complication rates. Conclusion. The laser technology and the introduction of small diameter semirigid and flexible ureteroscopes made ablation of upper urinary tract tumours possible and safe. Nevertheless a complete resection of the carcinomas is rarely possible.http://dx.doi.org/10.1155/2013/429585 |
| spellingShingle | Christos Kalaitzis Athanasios Zisimopoulos Stilianos Giannakopoulos Stavros Touloupidis Ureteroscopic Laser Treatment of Upper Urinary Tract Urothelial Cell Carcinomas: Can a Tumour Free Status Be Achieved? Advances in Urology |
| title | Ureteroscopic Laser Treatment of Upper Urinary Tract Urothelial Cell Carcinomas: Can a Tumour Free Status Be Achieved? |
| title_full | Ureteroscopic Laser Treatment of Upper Urinary Tract Urothelial Cell Carcinomas: Can a Tumour Free Status Be Achieved? |
| title_fullStr | Ureteroscopic Laser Treatment of Upper Urinary Tract Urothelial Cell Carcinomas: Can a Tumour Free Status Be Achieved? |
| title_full_unstemmed | Ureteroscopic Laser Treatment of Upper Urinary Tract Urothelial Cell Carcinomas: Can a Tumour Free Status Be Achieved? |
| title_short | Ureteroscopic Laser Treatment of Upper Urinary Tract Urothelial Cell Carcinomas: Can a Tumour Free Status Be Achieved? |
| title_sort | ureteroscopic laser treatment of upper urinary tract urothelial cell carcinomas can a tumour free status be achieved |
| url | http://dx.doi.org/10.1155/2013/429585 |
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