Utility of [18F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan in Inflammatory Myopathies: Case Report and Literature Review
Introduction. Inflammatory myopathies are a rare group of diseases characterized by proximal weakness. Incidence ranges from 7.98/million/year and prevalence at 14/100,000. The utility of [18F] fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) scan is increasing fo...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2018/8398453 |
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| author | Juan Pablo Rivas-de Noriega Javier Andrés Galnares-Olalde Javier Zúñiga-Varga Juan Pablo Herrera-Félix Marco Antonio Alegría-Loyola Alonso Turrent-Carriles |
| author_facet | Juan Pablo Rivas-de Noriega Javier Andrés Galnares-Olalde Javier Zúñiga-Varga Juan Pablo Herrera-Félix Marco Antonio Alegría-Loyola Alonso Turrent-Carriles |
| author_sort | Juan Pablo Rivas-de Noriega |
| collection | DOAJ |
| description | Introduction. Inflammatory myopathies are a rare group of diseases characterized by proximal weakness. Incidence ranges from 7.98/million/year and prevalence at 14/100,000. The utility of [18F] fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) scan is increasing for the complementary diagnosis of myopathies. Case Report. An 84-year-old male was admitted with a history of difficulty rising from a chair and a fall. Laboratory results showed increased creatine kinase levels of more than 50 times the normal reference values. Electromyography (EMG) showed myopathic changes, and FDG-PET/CT scan showed increased FDG uptake in bilateral quadriceps. A biopsy was performed revealing lymphocytic predominant infiltrates and myonecrosis. Prednisone and intravenous immunoglobulin (IVIG) were administered with strength improvement. The patient was discharged for further follow-up. Discussion. FDG-PET/CT in inflammatory diseases has proven useful as muscle fibers have increased FDG uptake. In some cases, FDG-PET/CT is also useful in determining associated neoplastic diseases. |
| format | Article |
| id | doaj-art-c2599eeab4c5410188157cdc4b4223a9 |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-c2599eeab4c5410188157cdc4b4223a92025-02-03T01:24:20ZengWileyCase Reports in Rheumatology2090-68892090-68972018-01-01201810.1155/2018/83984538398453Utility of [18F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan in Inflammatory Myopathies: Case Report and Literature ReviewJuan Pablo Rivas-de Noriega0Javier Andrés Galnares-Olalde1Javier Zúñiga-Varga2Juan Pablo Herrera-Félix3Marco Antonio Alegría-Loyola4Alonso Turrent-Carriles5Internal Medicine Service, The American British Cowdray Medical Center IAP, Mexico City, MexicoInternal Medicine Service, The American British Cowdray Medical Center IAP, Mexico City, MexicoNephrology Service, The American British Cowdray Medical Center IAP, Mexico City, MexicoNephrology Service, The American British Cowdray Medical Center IAP, Mexico City, MexicoNeurology Service, The American British Cowdray Medical Center IAP, Mexico City, MexicoRheumatology Service, The American British Cowdray Medical Center IAP, Mexico City, MexicoIntroduction. Inflammatory myopathies are a rare group of diseases characterized by proximal weakness. Incidence ranges from 7.98/million/year and prevalence at 14/100,000. The utility of [18F] fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) scan is increasing for the complementary diagnosis of myopathies. Case Report. An 84-year-old male was admitted with a history of difficulty rising from a chair and a fall. Laboratory results showed increased creatine kinase levels of more than 50 times the normal reference values. Electromyography (EMG) showed myopathic changes, and FDG-PET/CT scan showed increased FDG uptake in bilateral quadriceps. A biopsy was performed revealing lymphocytic predominant infiltrates and myonecrosis. Prednisone and intravenous immunoglobulin (IVIG) were administered with strength improvement. The patient was discharged for further follow-up. Discussion. FDG-PET/CT in inflammatory diseases has proven useful as muscle fibers have increased FDG uptake. In some cases, FDG-PET/CT is also useful in determining associated neoplastic diseases.http://dx.doi.org/10.1155/2018/8398453 |
| spellingShingle | Juan Pablo Rivas-de Noriega Javier Andrés Galnares-Olalde Javier Zúñiga-Varga Juan Pablo Herrera-Félix Marco Antonio Alegría-Loyola Alonso Turrent-Carriles Utility of [18F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan in Inflammatory Myopathies: Case Report and Literature Review Case Reports in Rheumatology |
| title | Utility of [18F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan in Inflammatory Myopathies: Case Report and Literature Review |
| title_full | Utility of [18F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan in Inflammatory Myopathies: Case Report and Literature Review |
| title_fullStr | Utility of [18F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan in Inflammatory Myopathies: Case Report and Literature Review |
| title_full_unstemmed | Utility of [18F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan in Inflammatory Myopathies: Case Report and Literature Review |
| title_short | Utility of [18F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan in Inflammatory Myopathies: Case Report and Literature Review |
| title_sort | utility of 18f fluorodeoxyglucose positron emission tomography computed tomography scan in inflammatory myopathies case report and literature review |
| url | http://dx.doi.org/10.1155/2018/8398453 |
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