CML Developing Three Years after Therapy Completion in a Child with Ph(−) Pre-B-ALL

We report a girl with a history of Ph(−) pre-B-ALL and three years of disease-free survival admitting to our hospital for regular end of treatment checkup with an increased white blood cell count which in follow-up studies and molecular detection of BCR-ABL (p210) fusions gene had been diagnosed as...

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Main Authors: S. Hosseini, G. H. Bahoush, P. Vousogh, Sh. Ansari, Kh. Arjmandi, M. Sabzechian
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2011/670603
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author S. Hosseini
G. H. Bahoush
P. Vousogh
Sh. Ansari
Kh. Arjmandi
M. Sabzechian
author_facet S. Hosseini
G. H. Bahoush
P. Vousogh
Sh. Ansari
Kh. Arjmandi
M. Sabzechian
author_sort S. Hosseini
collection DOAJ
description We report a girl with a history of Ph(−) pre-B-ALL and three years of disease-free survival admitting to our hospital for regular end of treatment checkup with an increased white blood cell count which in follow-up studies and molecular detection of BCR-ABL (p210) fusions gene had been diagnosed as a Ph(+) typical CML. The upcoming question in this case scenario is whether developed CML is a secondary leukemia due to previous ALL chemotherapy or just a relapse case of primary leukemia.
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institution Kabale University
issn 2090-6560
2090-6579
language English
publishDate 2011-01-01
publisher Wiley
record_format Article
series Case Reports in Hematology
spelling doaj-art-c2347f04c31a485ea7f8b728ee5503162025-02-03T05:45:25ZengWileyCase Reports in Hematology2090-65602090-65792011-01-01201110.1155/2011/670603670603CML Developing Three Years after Therapy Completion in a Child with Ph(−) Pre-B-ALLS. Hosseini0G. H. Bahoush1P. Vousogh2Sh. Ansari3Kh. Arjmandi4M. Sabzechian5Hematology Laboratory, Hematology Oncology Ward, Ali Asghar Children Hospital, Tehran, IranHematology Laboratory, Hematology Oncology Ward, Ali Asghar Children Hospital, Tehran, IranHematology Laboratory, Hematology Oncology Ward, Ali Asghar Children Hospital, Tehran, IranHematology Laboratory, Hematology Oncology Ward, Ali Asghar Children Hospital, Tehran, IranTehran University of Medical Science, Tehran, IranTehran University of Medical Science, Tehran, IranWe report a girl with a history of Ph(−) pre-B-ALL and three years of disease-free survival admitting to our hospital for regular end of treatment checkup with an increased white blood cell count which in follow-up studies and molecular detection of BCR-ABL (p210) fusions gene had been diagnosed as a Ph(+) typical CML. The upcoming question in this case scenario is whether developed CML is a secondary leukemia due to previous ALL chemotherapy or just a relapse case of primary leukemia.http://dx.doi.org/10.1155/2011/670603
spellingShingle S. Hosseini
G. H. Bahoush
P. Vousogh
Sh. Ansari
Kh. Arjmandi
M. Sabzechian
CML Developing Three Years after Therapy Completion in a Child with Ph(−) Pre-B-ALL
Case Reports in Hematology
title CML Developing Three Years after Therapy Completion in a Child with Ph(−) Pre-B-ALL
title_full CML Developing Three Years after Therapy Completion in a Child with Ph(−) Pre-B-ALL
title_fullStr CML Developing Three Years after Therapy Completion in a Child with Ph(−) Pre-B-ALL
title_full_unstemmed CML Developing Three Years after Therapy Completion in a Child with Ph(−) Pre-B-ALL
title_short CML Developing Three Years after Therapy Completion in a Child with Ph(−) Pre-B-ALL
title_sort cml developing three years after therapy completion in a child with ph pre b all
url http://dx.doi.org/10.1155/2011/670603
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