Dehydrodiisoeugenol targets NOD2 exerting dual effects against colitis and colorectal cancer: a double-edged sword

Dehydrodiisoeugenol targets NOD2 exerting dual effects against colitis and colorectal cancer: a double-edged sword

Abstract Dehydrodiisoeugenol (DEH) is a primary benzofuran-type neolignan isolated from the Chinese herbal medicine nutmeg, which is used in the treatment of gastrointestinal diseases. This study aims to observe the dual therapeutic effects of DEH on DSS-induced ulcerative colitis (UC) and colorecta...

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Bibliographic Details
Main Authors: Feiyang Yi, Nianzhi Chen, Maoyuan Zhao, Zhili Gu, Yun Yuan, Xuegui Tang, Fang Liu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Molecular Medicine
Subjects:
Ulcerative colitis
Colorectal cancer
Dehydrodiisoeugenol
NOD2
Online Access:https://doi.org/10.1186/s10020-025-01193-7
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