Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression.

<h4>Background</h4>The use of temozolomide (TMZ) has improved the prognosis for glioblastoma multiforme patients. However, TMZ resistance may be one of the main reasons why treatment fails. Although this resistance has frequently been linked to the expression of O6-methylguanine-DNA meth...

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Bibliographic Details
Main Authors: Gloria Perazzoli, Jose Prados, Raul Ortiz, Octavio Caba, Laura Cabeza, Maria Berdasco, Beatriz Gónzalez, Consolación Melguizo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0140131&type=printable
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