Elucidating the immune landscape and potential prognostic model in acute myeloid leukemia with TP53 mutation

Elucidating the immune landscape and potential prognostic model in acute myeloid leukemia with TP53 mutation

Objectives The TP53 mutation, a prevalent tumor suppressor gene alteration, is linked to chemotherapy resistance, increased relapse rates and diminished overall survival (OS) in acute myeloid leukemia (AML) patients.Methods In this study, we characterize the TP53 mutation phenotypes across various A...

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Bibliographic Details
Main Authors: Gelan Zhu, Jiayi Cai, Wanbin Fu, Yue Sun, Ting Wang, Hua Zhong
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Hematology
Subjects:
Prognostic model
acute myeloid leukemia
immune landscape
TP53 mutation
Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2024.2400620
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