In-house isolation protocol from human serum samples demonstrates the circulating of a broad diversity of Leptospira serogroups in Costa Rica

Abstract The isolation of pathogenic Leptospira is fundamental for a comprehensive characterization of circulating strains in endemic regions. Unfortunately, culture methods of Leptospira spp. are laborious and challenging. Here, we present a method for the isolation of these pathogenic bacteria fro...

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Bibliographic Details
Main Authors: Diana Chinchilla, Inés Sánchez, Diego Montero, Mathieu Picardeau, Ricardo Gutiérrez
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-93301-0
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