Differential regulation of mTOR activity in retinal ganglion cells underlies their distinct susceptibility to ischemia/reperfusion
Abstract Retinal ischemia/reperfusion (I/R) injury drives progressive retinal ganglion cell (RGC) loss, yet mechanisms underlying neuronal type-specific vulnerability remain unclear. Using a mouse model of bilateral common carotid artery ligation, we observe decreased vessel density in the inner ret...
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| Main Authors: | Meizhen Zhu, Yuqing Wu, Hang Gao, Fujian Qi, Xiaoyu Zhang, Yanli Ran |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-06-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-08314-2 |
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