Current Update on DWI-MRI and Its Radiomics in Liver Fibrosis—A Review of the Literature

Introduction: Diffusion-weighted imaging (DWI) is a non-invasive technique for acquiring liver pathology data and characterizing liver lesions. This modality shows promise for applications in the initial diagnosis and monitoring of liver diseases, providing valuable insights for clinical assessment...

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Main Author: Ali S. Alyami
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Tomography
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Online Access:https://www.mdpi.com/2379-139X/11/6/63
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author Ali S. Alyami
author_facet Ali S. Alyami
author_sort Ali S. Alyami
collection DOAJ
description Introduction: Diffusion-weighted imaging (DWI) is a non-invasive technique for acquiring liver pathology data and characterizing liver lesions. This modality shows promise for applications in the initial diagnosis and monitoring of liver diseases, providing valuable insights for clinical assessment and treatment strategies. Intravoxel incoherent motion (IVIM), diffusion kurtosis imaging (DKI), and diffusion tensor imaging (DTI) are advanced forms of DWI. These techniques have proven effective for assessing liver lesions, including liver tumors and fibrosis. However, the results can be inconsistent. Thus, it is essential to summarize the current applications of these methods in liver fibrosis, identify existing limitations, and suggest future directions for development. Methods: This review assessed studies concerning liver DWI and its applications published in the PubMed database over the last nine years. It presents these techniques’ fundamental principles and key factors before discussing their application in liver fibrosis. Results and conclusions: It has been observed that advanced DWI sequences remain unreliable in ensuring the robustness and reproducibility of measurements when assessing liver fibrosis grades, due to inconsistent results and significant overlap among these techniques across different stages of fibrotic conditions.
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spelling doaj-art-c2098ade8abf477f9ca0c563829b29ac2025-08-20T03:26:56ZengMDPI AGTomography2379-13812379-139X2025-05-011166310.3390/tomography11060063Current Update on DWI-MRI and Its Radiomics in Liver Fibrosis—A Review of the LiteratureAli S. Alyami0Department of Diagnostic Radiography Technology, College of Nursing and Health Sciences, Jazan University, Jazan 45142, Saudi ArabiaIntroduction: Diffusion-weighted imaging (DWI) is a non-invasive technique for acquiring liver pathology data and characterizing liver lesions. This modality shows promise for applications in the initial diagnosis and monitoring of liver diseases, providing valuable insights for clinical assessment and treatment strategies. Intravoxel incoherent motion (IVIM), diffusion kurtosis imaging (DKI), and diffusion tensor imaging (DTI) are advanced forms of DWI. These techniques have proven effective for assessing liver lesions, including liver tumors and fibrosis. However, the results can be inconsistent. Thus, it is essential to summarize the current applications of these methods in liver fibrosis, identify existing limitations, and suggest future directions for development. Methods: This review assessed studies concerning liver DWI and its applications published in the PubMed database over the last nine years. It presents these techniques’ fundamental principles and key factors before discussing their application in liver fibrosis. Results and conclusions: It has been observed that advanced DWI sequences remain unreliable in ensuring the robustness and reproducibility of measurements when assessing liver fibrosis grades, due to inconsistent results and significant overlap among these techniques across different stages of fibrotic conditions.https://www.mdpi.com/2379-139X/11/6/63liver fibrosisassessmentDWIIVIM-DWI
spellingShingle Ali S. Alyami
Current Update on DWI-MRI and Its Radiomics in Liver Fibrosis—A Review of the Literature
Tomography
liver fibrosis
assessment
DWI
IVIM-DWI
title Current Update on DWI-MRI and Its Radiomics in Liver Fibrosis—A Review of the Literature
title_full Current Update on DWI-MRI and Its Radiomics in Liver Fibrosis—A Review of the Literature
title_fullStr Current Update on DWI-MRI and Its Radiomics in Liver Fibrosis—A Review of the Literature
title_full_unstemmed Current Update on DWI-MRI and Its Radiomics in Liver Fibrosis—A Review of the Literature
title_short Current Update on DWI-MRI and Its Radiomics in Liver Fibrosis—A Review of the Literature
title_sort current update on dwi mri and its radiomics in liver fibrosis a review of the literature
topic liver fibrosis
assessment
DWI
IVIM-DWI
url https://www.mdpi.com/2379-139X/11/6/63
work_keys_str_mv AT alisalyami currentupdateondwimrianditsradiomicsinliverfibrosisareviewoftheliterature