Perivascular cerebrospinal fluid inflow matches interstitial fluid efflux in anesthetized rats
Summary: Waste solutes are cleared from the brain via outflow of interstitial fluid (ISF). Blood-brain barrier (BBB) water secretion and inflow of cerebrospinal fluid (CSF) via perivascular channels have been suggested as potential fluid sources to replace outflowing ISF. To assess the role of CSF i...
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| Main Authors: | Kristian N. Mortensen, Tuomas Lilius, Marko Rosenholm, Björn Sigurðsson, Douglas H. Kelley, Maiken Nedergaard |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
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| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S258900422500584X |
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