Perivascular cerebrospinal fluid inflow matches interstitial fluid efflux in anesthetized rats

Summary: Waste solutes are cleared from the brain via outflow of interstitial fluid (ISF). Blood-brain barrier (BBB) water secretion and inflow of cerebrospinal fluid (CSF) via perivascular channels have been suggested as potential fluid sources to replace outflowing ISF. To assess the role of CSF i...

Full description

Saved in:
Bibliographic Details
Main Authors: Kristian N. Mortensen, Tuomas Lilius, Marko Rosenholm, Björn Sigurðsson, Douglas H. Kelley, Maiken Nedergaard
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422500584X
Tags: Add Tag
No Tags, Be the first to tag this record!