Hepatitis B virus infections in pregnant women and children in the era of HBV elimination
In the hepatitis B virus (HBV) elimination strategy announced by the World Health Organization (WHO) in 2016, one of the main aspects is the prevention of vertical infections. In the prevention of vertical HBV infections, chemoprophylaxis with tenofovir is recommended from the 28 th week of pregnan...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2024-12-01
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| Series: | Clinical & Experimental Hepatology |
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| Online Access: | https://www.termedia.pl/Hepatitis-B-virus-infections-in-pregnant-women-and-children-in-the-era-of-HBV-elimination,80,55212,1,1.html |
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| _version_ | 1832584887729651712 |
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| author | Malgorzata Pawlowska |
| author_facet | Malgorzata Pawlowska |
| author_sort | Malgorzata Pawlowska |
| collection | DOAJ |
| description | In the hepatitis B virus (HBV) elimination strategy announced by the World Health Organization (WHO) in 2016, one of the main aspects is the prevention of vertical infections. In the prevention of vertical HBV infections, chemoprophylaxis with tenofovir is recommended from the 28 th week of pregnancy in women with a high viral load (HBV DNA > 2 × 10 5 IU/ml) or the presence of HBeAg in the serum and active-passive immunoprophylaxis (HepB-BD+ HBIG) in all newborns born to mothers infected with HBV. Attention was paid to the incidence of latent HBV infections among children and adolescents and the role of the vaccine dose and additional hepatitis B booster vaccination in the prevention of HBV, especially in highly endemic areas and risk groups. The role of the age of initiation of therapy in the context of functional cure was indicated. |
| format | Article |
| id | doaj-art-c1e6305bebdd4b3f8b6646d959d370ea |
| institution | Kabale University |
| issn | 2392-1099 2449-8238 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Clinical & Experimental Hepatology |
| spelling | doaj-art-c1e6305bebdd4b3f8b6646d959d370ea2025-01-27T10:31:14ZengTermedia Publishing HouseClinical & Experimental Hepatology2392-10992449-82382024-12-0110422723110.5114/ceh.2024.14536455212Hepatitis B virus infections in pregnant women and children in the era of HBV eliminationMalgorzata PawlowskaIn the hepatitis B virus (HBV) elimination strategy announced by the World Health Organization (WHO) in 2016, one of the main aspects is the prevention of vertical infections. In the prevention of vertical HBV infections, chemoprophylaxis with tenofovir is recommended from the 28 th week of pregnancy in women with a high viral load (HBV DNA > 2 × 10 5 IU/ml) or the presence of HBeAg in the serum and active-passive immunoprophylaxis (HepB-BD+ HBIG) in all newborns born to mothers infected with HBV. Attention was paid to the incidence of latent HBV infections among children and adolescents and the role of the vaccine dose and additional hepatitis B booster vaccination in the prevention of HBV, especially in highly endemic areas and risk groups. The role of the age of initiation of therapy in the context of functional cure was indicated.https://www.termedia.pl/Hepatitis-B-virus-infections-in-pregnant-women-and-children-in-the-era-of-HBV-elimination,80,55212,1,1.htmlhbv vertical infections prevention occult hbv infections children |
| spellingShingle | Malgorzata Pawlowska Hepatitis B virus infections in pregnant women and children in the era of HBV elimination Clinical & Experimental Hepatology hbv vertical infections prevention occult hbv infections children |
| title | Hepatitis B virus infections in pregnant women and children in the era of HBV elimination |
| title_full | Hepatitis B virus infections in pregnant women and children in the era of HBV elimination |
| title_fullStr | Hepatitis B virus infections in pregnant women and children in the era of HBV elimination |
| title_full_unstemmed | Hepatitis B virus infections in pregnant women and children in the era of HBV elimination |
| title_short | Hepatitis B virus infections in pregnant women and children in the era of HBV elimination |
| title_sort | hepatitis b virus infections in pregnant women and children in the era of hbv elimination |
| topic | hbv vertical infections prevention occult hbv infections children |
| url | https://www.termedia.pl/Hepatitis-B-virus-infections-in-pregnant-women-and-children-in-the-era-of-HBV-elimination,80,55212,1,1.html |
| work_keys_str_mv | AT malgorzatapawlowska hepatitisbvirusinfectionsinpregnantwomenandchildrenintheeraofhbvelimination |