PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES
Abstract. We have studied some features of immune system in children with common episodes of acute respiratory infections accompanied by lymphadenopathies (LAP). Among this cohort of the patients, a decrease in general immune reactions was revealed, accomplished by polyclonal activation of distinct...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
|
| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/374 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849401384794849280 |
|---|---|
| author | N. N. Popov A. N. Savvo E. A. Romanova |
| author_facet | N. N. Popov A. N. Savvo E. A. Romanova |
| author_sort | N. N. Popov |
| collection | DOAJ |
| description | Abstract. We have studied some features of immune system in children with common episodes of acute respiratory infections accompanied by lymphadenopathies (LAP). Among this cohort of the patients, a decrease in general immune reactions was revealed, accomplished by polyclonal activation of distinct lymphocyte subpopulations. Certain immune changes have been discerned in children with common infections accompanied by a LAP syndrome, such as an increased ratios of T- and B-lymphocytes carrying CD69 and CD25 activation molecules, a CD71 marker typical for proliferating cells, NKT-cells positive for CD3, CD56, CD8 with high cytokine-producing potential, as well as increased rates of spontaneous blast transformation of lymphocytes, both in course of the disease, and following recovery of the children. |
| format | Article |
| id | doaj-art-c1dfbb5e084b4059a1eab26f0c778c35 |
| institution | Kabale University |
| issn | 1563-0625 2313-741X |
| language | Russian |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj-art-c1dfbb5e084b4059a1eab26f0c778c352025-08-20T03:37:46ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0111658158610.15789/1563-0625-2009-6-581-586371PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIESN. N. Popov0A. N. Savvo1E. A. Romanova2Харьковский национальный университет им. В.Н. Каразина, г. ХарьковХарьковский национальный университет им. В.Н. Каразина, г. ХарьковГУ «Институт микробиологии и иммунологии им. И.И. Мечникова АМН Украины», г. ХарьковAbstract. We have studied some features of immune system in children with common episodes of acute respiratory infections accompanied by lymphadenopathies (LAP). Among this cohort of the patients, a decrease in general immune reactions was revealed, accomplished by polyclonal activation of distinct lymphocyte subpopulations. Certain immune changes have been discerned in children with common infections accompanied by a LAP syndrome, such as an increased ratios of T- and B-lymphocytes carrying CD69 and CD25 activation molecules, a CD71 marker typical for proliferating cells, NKT-cells positive for CD3, CD56, CD8 with high cytokine-producing potential, as well as increased rates of spontaneous blast transformation of lymphocytes, both in course of the disease, and following recovery of the children.https://www.mimmun.ru/mimmun/article/view/374т-lymphocytesв-lymphocyteslymphocyte subpopulationsimmunitylymphadenopathieschildren |
| spellingShingle | N. N. Popov A. N. Savvo E. A. Romanova PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES Медицинская иммунология т-lymphocytes в-lymphocytes lymphocyte subpopulations immunity lymphadenopathies children |
| title | PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES |
| title_full | PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES |
| title_fullStr | PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES |
| title_full_unstemmed | PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES |
| title_short | PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES |
| title_sort | patterns of local and general immunity among children suffering from common illnesses accomplished by lymphadenopathies |
| topic | т-lymphocytes в-lymphocytes lymphocyte subpopulations immunity lymphadenopathies children |
| url | https://www.mimmun.ru/mimmun/article/view/374 |
| work_keys_str_mv | AT nnpopov patternsoflocalandgeneralimmunityamongchildrensufferingfromcommonillnessesaccomplishedbylymphadenopathies AT ansavvo patternsoflocalandgeneralimmunityamongchildrensufferingfromcommonillnessesaccomplishedbylymphadenopathies AT earomanova patternsoflocalandgeneralimmunityamongchildrensufferingfromcommonillnessesaccomplishedbylymphadenopathies |