An RNA transmethylation pathway governs kidney nephrogenic potential

Abstract The adult kidney lacks the ability to generate new nephrons, placing individuals born with low nephron counts at greater risk for chronic kidney disease as they age. Limited nutrient availability hinders nephron formation; however, the key metabolic dependencies remain unclear. Here we show...

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Bibliographic Details
Main Authors: Harini Ramalingam, Jesus Alvarez, Andrea Flaten, Patricia Cobo-Stark, Nicholas Foster, Elyse Grilli, Ronak Lakhia, Karam Aboudehen, Thomas Carroll, Vishal Patel
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60097-6
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