Tissue Specific Expression Levels of Apoptosis Involved Genes Have Correlations with Codon and Amino Acid Usage
Different mechanisms, including transcriptional and post transcriptional processes, regulate tissue specific expression of genes. In this study, we report differences in gene/protein compositional features between apoptosis involved genes selectively expressed in human tissues. We found some correla...
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| Format: | Article |
| Language: | English |
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BioMed Central
2016-12-01
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| Series: | Genomics & Informatics |
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| Online Access: | http://genominfo.org/upload/pdf/gni-14-234.pdf |
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| _version_ | 1832570586745798656 |
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| author | Mohammadreza Hajjari Iman Sadeghi Abbas Salavaty Habib Nasiri Maryam Tahmasebi Birgani |
| author_facet | Mohammadreza Hajjari Iman Sadeghi Abbas Salavaty Habib Nasiri Maryam Tahmasebi Birgani |
| author_sort | Mohammadreza Hajjari |
| collection | DOAJ |
| description | Different mechanisms, including transcriptional and post transcriptional processes, regulate tissue specific expression of genes. In this study, we report differences in gene/protein compositional features between apoptosis involved genes selectively expressed in human tissues. We found some correlations between codon/amino acid usage and tissue specific expression level of genes. The findings can be significant for understanding the translational selection on these features. The selection may play an important role in the differentiation of human tissues and can be considered for future studies in diagnosis of some diseases such as cancer. |
| format | Article |
| id | doaj-art-c19223cd49bc473fb6c37ec3eb51dcf3 |
| institution | Kabale University |
| issn | 1598-866X 2234-0742 |
| language | English |
| publishDate | 2016-12-01 |
| publisher | BioMed Central |
| record_format | Article |
| series | Genomics & Informatics |
| spelling | doaj-art-c19223cd49bc473fb6c37ec3eb51dcf32025-02-02T14:39:55ZengBioMed CentralGenomics & Informatics1598-866X2234-07422016-12-0114423424010.5808/GI.2016.14.4.234183Tissue Specific Expression Levels of Apoptosis Involved Genes Have Correlations with Codon and Amino Acid UsageMohammadreza Hajjari0Iman Sadeghi1Abbas Salavaty2Habib Nasiri3Maryam Tahmasebi Birgani4Department of Genetics, Faculty of Sciences, Shahid Chamran University of Ahvaz, Ahvaz 61357-83151, Iran.Department of Molecular Genetics, Faculty of Biosciences, Tarbiat Modares University of Tehran, Tehran 14115116, Iran.Department of Genetics, Faculty of Sciences, Shahid Chamran University of Ahvaz, Ahvaz 61357-83151, Iran.Department of Medical Genetics, Nika Center of Preventive Medicine and Health Promotion, Tehran 1418944711, Iran.Department of Medical Genetics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 61357-15794, Iran.Different mechanisms, including transcriptional and post transcriptional processes, regulate tissue specific expression of genes. In this study, we report differences in gene/protein compositional features between apoptosis involved genes selectively expressed in human tissues. We found some correlations between codon/amino acid usage and tissue specific expression level of genes. The findings can be significant for understanding the translational selection on these features. The selection may play an important role in the differentiation of human tissues and can be considered for future studies in diagnosis of some diseases such as cancer.http://genominfo.org/upload/pdf/gni-14-234.pdfapoptosiscodongene expression regulationtranslation |
| spellingShingle | Mohammadreza Hajjari Iman Sadeghi Abbas Salavaty Habib Nasiri Maryam Tahmasebi Birgani Tissue Specific Expression Levels of Apoptosis Involved Genes Have Correlations with Codon and Amino Acid Usage Genomics & Informatics apoptosis codon gene expression regulation translation |
| title | Tissue Specific Expression Levels of Apoptosis Involved Genes Have Correlations with Codon and Amino Acid Usage |
| title_full | Tissue Specific Expression Levels of Apoptosis Involved Genes Have Correlations with Codon and Amino Acid Usage |
| title_fullStr | Tissue Specific Expression Levels of Apoptosis Involved Genes Have Correlations with Codon and Amino Acid Usage |
| title_full_unstemmed | Tissue Specific Expression Levels of Apoptosis Involved Genes Have Correlations with Codon and Amino Acid Usage |
| title_short | Tissue Specific Expression Levels of Apoptosis Involved Genes Have Correlations with Codon and Amino Acid Usage |
| title_sort | tissue specific expression levels of apoptosis involved genes have correlations with codon and amino acid usage |
| topic | apoptosis codon gene expression regulation translation |
| url | http://genominfo.org/upload/pdf/gni-14-234.pdf |
| work_keys_str_mv | AT mohammadrezahajjari tissuespecificexpressionlevelsofapoptosisinvolvedgeneshavecorrelationswithcodonandaminoacidusage AT imansadeghi tissuespecificexpressionlevelsofapoptosisinvolvedgeneshavecorrelationswithcodonandaminoacidusage AT abbassalavaty tissuespecificexpressionlevelsofapoptosisinvolvedgeneshavecorrelationswithcodonandaminoacidusage AT habibnasiri tissuespecificexpressionlevelsofapoptosisinvolvedgeneshavecorrelationswithcodonandaminoacidusage AT maryamtahmasebibirgani tissuespecificexpressionlevelsofapoptosisinvolvedgeneshavecorrelationswithcodonandaminoacidusage |