Case Report: Sudden death caused by methylene chloride poisoning

Dichloromethane is widely used as an organic solvent in aerospace, electronics, and medicine. Cases of poisoning caused by this substance are rare. Recently, we successfully treated a patient with an acute dichloromethane poisoning. During the production process, owing to pipeline leakage and lack o...

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Main Authors: Ruikai Shang, Qiaoxin Tian, Yuru Liu, Hongyu Liu, Xiangxing Zhang, Mengdi Shi, Xiangdong Jian, Qilu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1471744/full
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author Ruikai Shang
Ruikai Shang
Qiaoxin Tian
Qiaoxin Tian
Yuru Liu
Hongyu Liu
Xiangxing Zhang
Xiangxing Zhang
Mengdi Shi
Mengdi Shi
Xiangdong Jian
Xiangdong Jian
Qilu Li
author_facet Ruikai Shang
Ruikai Shang
Qiaoxin Tian
Qiaoxin Tian
Yuru Liu
Hongyu Liu
Xiangxing Zhang
Xiangxing Zhang
Mengdi Shi
Mengdi Shi
Xiangdong Jian
Xiangdong Jian
Qilu Li
author_sort Ruikai Shang
collection DOAJ
description Dichloromethane is widely used as an organic solvent in aerospace, electronics, and medicine. Cases of poisoning caused by this substance are rare. Recently, we successfully treated a patient with an acute dichloromethane poisoning. During the production process, owing to pipeline leakage and lack of personal protection, the patient was poisoned by dichloromethane inhalation, fell from a height, and experienced a sudden cardiac arrest. After successful cardiopulmonary resuscitation, the patient was transferred to a local hospital for diagnosis and treatment and then to our hospital. After two visits to our hospital for systematic diagnosis and active treatment with fluid infusion, anti-infection therapy, glucocorticoids, ventilator-assisted respiration, chest strap fixation, and nutritional support, the patient achieved clinical recovery.
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institution OA Journals
issn 1663-9812
language English
publishDate 2024-11-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Pharmacology
spelling doaj-art-c16bca7a7ff94f2eb9f3067c4d1b7c072025-08-20T02:22:40ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122024-11-011510.3389/fphar.2024.14717441471744Case Report: Sudden death caused by methylene chloride poisoningRuikai Shang0Ruikai Shang1Qiaoxin Tian2Qiaoxin Tian3Yuru Liu4Hongyu Liu5Xiangxing Zhang6Xiangxing Zhang7Mengdi Shi8Mengdi Shi9Xiangdong Jian10Xiangdong Jian11Qilu Li12Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaSchool of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Pharmacy, the Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDichloromethane is widely used as an organic solvent in aerospace, electronics, and medicine. Cases of poisoning caused by this substance are rare. Recently, we successfully treated a patient with an acute dichloromethane poisoning. During the production process, owing to pipeline leakage and lack of personal protection, the patient was poisoned by dichloromethane inhalation, fell from a height, and experienced a sudden cardiac arrest. After successful cardiopulmonary resuscitation, the patient was transferred to a local hospital for diagnosis and treatment and then to our hospital. After two visits to our hospital for systematic diagnosis and active treatment with fluid infusion, anti-infection therapy, glucocorticoids, ventilator-assisted respiration, chest strap fixation, and nutritional support, the patient achieved clinical recovery.https://www.frontiersin.org/articles/10.3389/fphar.2024.1471744/fulldichloromethaneacute poisoningeventsfractured ribscardiopulmonary resuscitationcure
spellingShingle Ruikai Shang
Ruikai Shang
Qiaoxin Tian
Qiaoxin Tian
Yuru Liu
Hongyu Liu
Xiangxing Zhang
Xiangxing Zhang
Mengdi Shi
Mengdi Shi
Xiangdong Jian
Xiangdong Jian
Qilu Li
Case Report: Sudden death caused by methylene chloride poisoning
Frontiers in Pharmacology
dichloromethane
acute poisoning
events
fractured ribs
cardiopulmonary resuscitation
cure
title Case Report: Sudden death caused by methylene chloride poisoning
title_full Case Report: Sudden death caused by methylene chloride poisoning
title_fullStr Case Report: Sudden death caused by methylene chloride poisoning
title_full_unstemmed Case Report: Sudden death caused by methylene chloride poisoning
title_short Case Report: Sudden death caused by methylene chloride poisoning
title_sort case report sudden death caused by methylene chloride poisoning
topic dichloromethane
acute poisoning
events
fractured ribs
cardiopulmonary resuscitation
cure
url https://www.frontiersin.org/articles/10.3389/fphar.2024.1471744/full
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