An Efficient and Recycling Catalyst for the One-Pot Three-Component Synthesis of Substituted 3,4-Dihydropyrimidin-2(1H)-ones
The Biginelli one-pot three-component cyclocondensation was applied in this work to prepare 3,4-dihydropyrimidinone and its analogues using the first derivative of lead, Pb(NO3)2, as a recycling catalyst, from a diversity of aromatic aldehydes, β-ketoesters and urea. The reaction was carried out...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2008-01-01
|
| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2008/132879 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832554313484861440 |
|---|---|
| author | Taoues Boumoud Boudjemaa Boumoud Salah Rhouati Ali Belfaitah Abdelmadjid Debache Paul Mosset |
| author_facet | Taoues Boumoud Boudjemaa Boumoud Salah Rhouati Ali Belfaitah Abdelmadjid Debache Paul Mosset |
| author_sort | Taoues Boumoud |
| collection | DOAJ |
| description | The Biginelli one-pot three-component cyclocondensation was applied in this work to prepare 3,4-dihydropyrimidinone and its analogues using the first derivative of lead, Pb(NO3)2, as a recycling catalyst, from a diversity of aromatic aldehydes, β-ketoesters and urea. The reaction was carried out in refluxing acetonitrile and afforded the target molecules in good to excellent yields. The method offers several advantages including high yields of the products, short reaction times and easy experimental workup procedure |
| format | Article |
| id | doaj-art-c16ba826851244fd9d85e8e4b3810e3f |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2008-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-c16ba826851244fd9d85e8e4b3810e3f2025-02-03T05:51:48ZengWileyE-Journal of Chemistry0973-49452090-98102008-01-015468869510.1155/2008/132879An Efficient and Recycling Catalyst for the One-Pot Three-Component Synthesis of Substituted 3,4-Dihydropyrimidin-2(1H)-onesTaoues Boumoud0Boudjemaa Boumoud1Salah Rhouati2Ali Belfaitah3Abdelmadjid Debache4Paul Mosset5Laboratoire des Produits Naturels d’origine Végétale et de Synthèse Organique. Département de Chimie. Faculté des Sciences. Universit Mentouri de Constantine 25000 Constantine, AlgeriaLaboratoire des Produits Naturels d’origine Végétale et de Synthèse Organique. Département de Chimie. Faculté des Sciences. Universit Mentouri de Constantine 25000 Constantine, AlgeriaLaboratoire des Produits Naturels d’origine Végétale et de Synthèse Organique. Département de Chimie. Faculté des Sciences. Universit Mentouri de Constantine 25000 Constantine, AlgeriaLaboratoire des Produits Naturels d’origine Végétale et de Synthèse Organique. Département de Chimie. Faculté des Sciences. Universit Mentouri de Constantine 25000 Constantine, AlgeriaLaboratoire des Produits Naturels d’origine Végétale et de Synthèse Organique. Département de Chimie. Faculté des Sciences. Universit Mentouri de Constantine 25000 Constantine, AlgeriaLaboratoire des Produits Naturels d’origine Végétale et de Synthèse Organique. Département de Chimie. Faculté des Sciences. Universit Mentouri de Constantine 25000 Constantine, AlgeriaThe Biginelli one-pot three-component cyclocondensation was applied in this work to prepare 3,4-dihydropyrimidinone and its analogues using the first derivative of lead, Pb(NO3)2, as a recycling catalyst, from a diversity of aromatic aldehydes, β-ketoesters and urea. The reaction was carried out in refluxing acetonitrile and afforded the target molecules in good to excellent yields. The method offers several advantages including high yields of the products, short reaction times and easy experimental workup procedurehttp://dx.doi.org/10.1155/2008/132879 |
| spellingShingle | Taoues Boumoud Boudjemaa Boumoud Salah Rhouati Ali Belfaitah Abdelmadjid Debache Paul Mosset An Efficient and Recycling Catalyst for the One-Pot Three-Component Synthesis of Substituted 3,4-Dihydropyrimidin-2(1H)-ones E-Journal of Chemistry |
| title | An Efficient and Recycling Catalyst for the One-Pot Three-Component Synthesis of Substituted 3,4-Dihydropyrimidin-2(1H)-ones |
| title_full | An Efficient and Recycling Catalyst for the One-Pot Three-Component Synthesis of Substituted 3,4-Dihydropyrimidin-2(1H)-ones |
| title_fullStr | An Efficient and Recycling Catalyst for the One-Pot Three-Component Synthesis of Substituted 3,4-Dihydropyrimidin-2(1H)-ones |
| title_full_unstemmed | An Efficient and Recycling Catalyst for the One-Pot Three-Component Synthesis of Substituted 3,4-Dihydropyrimidin-2(1H)-ones |
| title_short | An Efficient and Recycling Catalyst for the One-Pot Three-Component Synthesis of Substituted 3,4-Dihydropyrimidin-2(1H)-ones |
| title_sort | efficient and recycling catalyst for the one pot three component synthesis of substituted 3 4 dihydropyrimidin 2 1h ones |
| url | http://dx.doi.org/10.1155/2008/132879 |
| work_keys_str_mv | AT taouesboumoud anefficientandrecyclingcatalystfortheonepotthreecomponentsynthesisofsubstituted34dihydropyrimidin21hones AT boudjemaaboumoud anefficientandrecyclingcatalystfortheonepotthreecomponentsynthesisofsubstituted34dihydropyrimidin21hones AT salahrhouati anefficientandrecyclingcatalystfortheonepotthreecomponentsynthesisofsubstituted34dihydropyrimidin21hones AT alibelfaitah anefficientandrecyclingcatalystfortheonepotthreecomponentsynthesisofsubstituted34dihydropyrimidin21hones AT abdelmadjiddebache anefficientandrecyclingcatalystfortheonepotthreecomponentsynthesisofsubstituted34dihydropyrimidin21hones AT paulmosset anefficientandrecyclingcatalystfortheonepotthreecomponentsynthesisofsubstituted34dihydropyrimidin21hones AT taouesboumoud efficientandrecyclingcatalystfortheonepotthreecomponentsynthesisofsubstituted34dihydropyrimidin21hones AT boudjemaaboumoud efficientandrecyclingcatalystfortheonepotthreecomponentsynthesisofsubstituted34dihydropyrimidin21hones AT salahrhouati efficientandrecyclingcatalystfortheonepotthreecomponentsynthesisofsubstituted34dihydropyrimidin21hones AT alibelfaitah efficientandrecyclingcatalystfortheonepotthreecomponentsynthesisofsubstituted34dihydropyrimidin21hones AT abdelmadjiddebache efficientandrecyclingcatalystfortheonepotthreecomponentsynthesisofsubstituted34dihydropyrimidin21hones AT paulmosset efficientandrecyclingcatalystfortheonepotthreecomponentsynthesisofsubstituted34dihydropyrimidin21hones |