Association of insomnia with suicide attempts in Chinese chronic schizophrenia patients with and without autistic symptoms
Abstract Background Numerous studies have shown that people with schizophrenia (SCZ) have a higher risk of suicide, and insomnia symptoms are common in SCZ patients. Autism symptoms (AS) are common in SCZ patients, and they are strongly linked to suicide. This study explored the connection between i...
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| Language: | English |
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BMC
2025-07-01
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| Series: | BMC Psychiatry |
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| Online Access: | https://doi.org/10.1186/s12888-025-07031-8 |
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| author | Wenzheng Li Yu Liu Rui Tao Long Chen Yang Liu Daming Mo Huanzhong Liu Xiangyang Zhang |
| author_facet | Wenzheng Li Yu Liu Rui Tao Long Chen Yang Liu Daming Mo Huanzhong Liu Xiangyang Zhang |
| author_sort | Wenzheng Li |
| collection | DOAJ |
| description | Abstract Background Numerous studies have shown that people with schizophrenia (SCZ) have a higher risk of suicide, and insomnia symptoms are common in SCZ patients. Autism symptoms (AS) are common in SCZ patients, and they are strongly linked to suicide. This study explored the connection between insomnia, autistic symptoms, and suicide attempts in Chinese patients with SCZ, it has not yet been investigated. Methods 955 Chinese chronic SCZ patients provided demographic and clinical information for data collection. Insomnia Symptom Severity Index (ISI) was used to assess the severity of insomnia symptoms, and Beck Scale for Suicide Ideation (BSS) was used to assess the risk of suicide. PANSS Autism Severity Score (PAUSS) was used to assess autistic symptoms. Results The incidence of insomnia was higher in AS-SCZ patients than in non-AS-SCZ patients, but the incidence of suicide attempts was lower than that in non-AS-SCZ patients (all p < 0.05). In SCZ patients, insomnia severity scores were strongly associated with suicide attempts. Further correlational analysis showed that this association was only present in non-AS-SCZ patients (p < 0.05). Conclusions Insomnia in patients with chronic SCZ may be influenced by autistic symptoms, potentially impacting the association between suicide attempts and insomnia. Trial registration The study was a cross-sectional study, so there was no clinical trial registration. Clinical trial number: not applicable. |
| format | Article |
| id | doaj-art-c16b561899794b92b34b66c281ed4f8f |
| institution | Kabale University |
| issn | 1471-244X |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Psychiatry |
| spelling | doaj-art-c16b561899794b92b34b66c281ed4f8f2025-08-20T04:01:40ZengBMCBMC Psychiatry1471-244X2025-07-012511910.1186/s12888-025-07031-8Association of insomnia with suicide attempts in Chinese chronic schizophrenia patients with and without autistic symptomsWenzheng Li0Yu Liu1Rui Tao2Long Chen3Yang Liu4Daming Mo5Huanzhong Liu6Xiangyang Zhang7Hefei Fourth People’s HospitalHefei Fourth People’s HospitalDepartment of Psychiatry, Chao Hu Hospital of Anhui Medical UniversityHefei Fourth People’s HospitalHefei Fourth People’s HospitalHefei Fourth People’s HospitalDepartment of Psychiatry, Chao Hu Hospital of Anhui Medical UniversityHefei Fourth People’s HospitalAbstract Background Numerous studies have shown that people with schizophrenia (SCZ) have a higher risk of suicide, and insomnia symptoms are common in SCZ patients. Autism symptoms (AS) are common in SCZ patients, and they are strongly linked to suicide. This study explored the connection between insomnia, autistic symptoms, and suicide attempts in Chinese patients with SCZ, it has not yet been investigated. Methods 955 Chinese chronic SCZ patients provided demographic and clinical information for data collection. Insomnia Symptom Severity Index (ISI) was used to assess the severity of insomnia symptoms, and Beck Scale for Suicide Ideation (BSS) was used to assess the risk of suicide. PANSS Autism Severity Score (PAUSS) was used to assess autistic symptoms. Results The incidence of insomnia was higher in AS-SCZ patients than in non-AS-SCZ patients, but the incidence of suicide attempts was lower than that in non-AS-SCZ patients (all p < 0.05). In SCZ patients, insomnia severity scores were strongly associated with suicide attempts. Further correlational analysis showed that this association was only present in non-AS-SCZ patients (p < 0.05). Conclusions Insomnia in patients with chronic SCZ may be influenced by autistic symptoms, potentially impacting the association between suicide attempts and insomnia. Trial registration The study was a cross-sectional study, so there was no clinical trial registration. Clinical trial number: not applicable.https://doi.org/10.1186/s12888-025-07031-8Suicide attemptsAutistic symptomsInsomniaSchizophrenia |
| spellingShingle | Wenzheng Li Yu Liu Rui Tao Long Chen Yang Liu Daming Mo Huanzhong Liu Xiangyang Zhang Association of insomnia with suicide attempts in Chinese chronic schizophrenia patients with and without autistic symptoms BMC Psychiatry Suicide attempts Autistic symptoms Insomnia Schizophrenia |
| title | Association of insomnia with suicide attempts in Chinese chronic schizophrenia patients with and without autistic symptoms |
| title_full | Association of insomnia with suicide attempts in Chinese chronic schizophrenia patients with and without autistic symptoms |
| title_fullStr | Association of insomnia with suicide attempts in Chinese chronic schizophrenia patients with and without autistic symptoms |
| title_full_unstemmed | Association of insomnia with suicide attempts in Chinese chronic schizophrenia patients with and without autistic symptoms |
| title_short | Association of insomnia with suicide attempts in Chinese chronic schizophrenia patients with and without autistic symptoms |
| title_sort | association of insomnia with suicide attempts in chinese chronic schizophrenia patients with and without autistic symptoms |
| topic | Suicide attempts Autistic symptoms Insomnia Schizophrenia |
| url | https://doi.org/10.1186/s12888-025-07031-8 |
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