Kinetics and Mechanism of Oxidation of Carbenicillin by Copper (III) Periodate Complex in Aqueous Alkaline Medium
Kinetics and mechanism of oxidation of carbenicillin by diperiodatocuprate [DPC-III] in aqueous alkaline medium were studied spectrophotometrically at 298 K and an ionic strength of 0.10 mol·dm−3. The reaction between DPC (III) and carbenicillin in the alkaline medium showed (CRBC : DPC-III) 1 : 4 s...
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Wiley
2020-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2020/4060984 |
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| author | Yuv Raj Sahu Parashuram Mishra |
| author_facet | Yuv Raj Sahu Parashuram Mishra |
| author_sort | Yuv Raj Sahu |
| collection | DOAJ |
| description | Kinetics and mechanism of oxidation of carbenicillin by diperiodatocuprate [DPC-III] in aqueous alkaline medium were studied spectrophotometrically at 298 K and an ionic strength of 0.10 mol·dm−3. The reaction between DPC (III) and carbenicillin in the alkaline medium showed (CRBC : DPC-III) 1 : 4 stoichiometry. The reaction products were identified by the CHNS test, FT-IR, and LC-MS spectral reports. The reaction was of pseudo-first order with respect to DPC (III) and fractional order with respect to carbenicillin as well as alkali but retarding effect with respect to periodate. Monoperiodatocuprate (MPC-III) was found to be the main active species in the alkaline medium in the form of [Cu (H2IO6) (H2O)2]. Activation and thermodynamic parameters with respect to uncatalyzed rate constants (ku) and slow step rate constant (k) as well as equilibrium constants were determined. The plausible mechanism consistent with experimental results was proposed and discussed in detail. |
| format | Article |
| id | doaj-art-c16a5acde041429faefd145b8ca754b7 |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
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| series | Journal of Chemistry |
| spelling | doaj-art-c16a5acde041429faefd145b8ca754b72025-02-03T01:27:54ZengWileyJournal of Chemistry2090-90632090-90712020-01-01202010.1155/2020/40609844060984Kinetics and Mechanism of Oxidation of Carbenicillin by Copper (III) Periodate Complex in Aqueous Alkaline MediumYuv Raj Sahu0Parashuram Mishra1Bio-Inorganic and Materials Chemistry Research Laboratory, Department of Chemistry, Mahendra Morang Adarsha Multiple Campus, Biratnagar, Tribhuwan University, NepalBio-Inorganic and Materials Chemistry Research Laboratory, Department of Chemistry, Mahendra Morang Adarsha Multiple Campus, Biratnagar, Tribhuwan University, NepalKinetics and mechanism of oxidation of carbenicillin by diperiodatocuprate [DPC-III] in aqueous alkaline medium were studied spectrophotometrically at 298 K and an ionic strength of 0.10 mol·dm−3. The reaction between DPC (III) and carbenicillin in the alkaline medium showed (CRBC : DPC-III) 1 : 4 stoichiometry. The reaction products were identified by the CHNS test, FT-IR, and LC-MS spectral reports. The reaction was of pseudo-first order with respect to DPC (III) and fractional order with respect to carbenicillin as well as alkali but retarding effect with respect to periodate. Monoperiodatocuprate (MPC-III) was found to be the main active species in the alkaline medium in the form of [Cu (H2IO6) (H2O)2]. Activation and thermodynamic parameters with respect to uncatalyzed rate constants (ku) and slow step rate constant (k) as well as equilibrium constants were determined. The plausible mechanism consistent with experimental results was proposed and discussed in detail.http://dx.doi.org/10.1155/2020/4060984 |
| spellingShingle | Yuv Raj Sahu Parashuram Mishra Kinetics and Mechanism of Oxidation of Carbenicillin by Copper (III) Periodate Complex in Aqueous Alkaline Medium Journal of Chemistry |
| title | Kinetics and Mechanism of Oxidation of Carbenicillin by Copper (III) Periodate Complex in Aqueous Alkaline Medium |
| title_full | Kinetics and Mechanism of Oxidation of Carbenicillin by Copper (III) Periodate Complex in Aqueous Alkaline Medium |
| title_fullStr | Kinetics and Mechanism of Oxidation of Carbenicillin by Copper (III) Periodate Complex in Aqueous Alkaline Medium |
| title_full_unstemmed | Kinetics and Mechanism of Oxidation of Carbenicillin by Copper (III) Periodate Complex in Aqueous Alkaline Medium |
| title_short | Kinetics and Mechanism of Oxidation of Carbenicillin by Copper (III) Periodate Complex in Aqueous Alkaline Medium |
| title_sort | kinetics and mechanism of oxidation of carbenicillin by copper iii periodate complex in aqueous alkaline medium |
| url | http://dx.doi.org/10.1155/2020/4060984 |
| work_keys_str_mv | AT yuvrajsahu kineticsandmechanismofoxidationofcarbenicillinbycopperiiiperiodatecomplexinaqueousalkalinemedium AT parashurammishra kineticsandmechanismofoxidationofcarbenicillinbycopperiiiperiodatecomplexinaqueousalkalinemedium |