Comprehensive comparison of the third-generation sequencing tools for bacterial 6mA profiling

Comprehensive comparison of the third-generation sequencing tools for bacterial 6mA profiling

Abstract DNA N6-methyladenine (6mA) serves as an intrinsic and principal epigenetic marker in prokaryotes, impacting various biological processes. To date, limited advanced sequencing technologies and analyzing tools are available for bacterial DNA 6mA. Here, we evaluate eight tools designed for the...

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Bibliographic Details
Main Authors: Beifang Lu, Zhihao Guo, Xudong Liu, Ying Ni, Letong Xu, Jiadai Huang, Tianmin Li, Tongtong Feng, Runsheng Li, Xin Deng
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59187-2
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