Pathological Mechanism and Clinical Therapy Progress of Schlemm’s Canal
Schlemm’s canal (SC) is a small circular canal in the deep part of the sclera at the junction of the sclera and cornea. As an integral component of the aqueous humor outflow, its structure and function are essential in regulating intraocular pressure (IOP). If SC develops lesions, the drainage of aq...
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Format: | Article |
Language: | English |
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Wiley
2024-01-01
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Series: | Journal of Ophthalmology |
Online Access: | http://dx.doi.org/10.1155/2024/9978312 |
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author | Yasha Zhou Zhenxin Liu Wenyong Gao Yijing Yang Qinghua Peng Hanyu Tan |
author_facet | Yasha Zhou Zhenxin Liu Wenyong Gao Yijing Yang Qinghua Peng Hanyu Tan |
author_sort | Yasha Zhou |
collection | DOAJ |
description | Schlemm’s canal (SC) is a small circular canal in the deep part of the sclera at the junction of the sclera and cornea. As an integral component of the aqueous humor outflow, its structure and function are essential in regulating intraocular pressure (IOP). If SC develops lesions, the drainage of aqueous humor would be obstructed, leading to increased intraocular pressure and injury to the optic nerve. With the rapid development of minimally invasive glaucoma surgery, an increasing number of surgeons became familiar with SC, and the area generated substantial academic attention. The pathological mechanism and the therapy for SC that had been studied in recent years are summarized in this article, hoping to provide ideas for the treatment of glaucoma in the future. |
format | Article |
id | doaj-art-c13a33c618384257af0ce0da3e047136 |
institution | Kabale University |
issn | 2090-0058 |
language | English |
publishDate | 2024-01-01 |
publisher | Wiley |
record_format | Article |
series | Journal of Ophthalmology |
spelling | doaj-art-c13a33c618384257af0ce0da3e0471362025-02-03T06:45:01ZengWileyJournal of Ophthalmology2090-00582024-01-01202410.1155/2024/9978312Pathological Mechanism and Clinical Therapy Progress of Schlemm’s CanalYasha Zhou0Zhenxin Liu1Wenyong Gao2Yijing Yang3Qinghua Peng4Hanyu Tan5Hunan University of Chinese MedicineHunan University of Chinese MedicineUbon Ratchathani UniversityHunan University of Chinese MedicineHunan University of Chinese MedicineYueyang Hospital Afiliated to Hunan University of Chinese MedicineSchlemm’s canal (SC) is a small circular canal in the deep part of the sclera at the junction of the sclera and cornea. As an integral component of the aqueous humor outflow, its structure and function are essential in regulating intraocular pressure (IOP). If SC develops lesions, the drainage of aqueous humor would be obstructed, leading to increased intraocular pressure and injury to the optic nerve. With the rapid development of minimally invasive glaucoma surgery, an increasing number of surgeons became familiar with SC, and the area generated substantial academic attention. The pathological mechanism and the therapy for SC that had been studied in recent years are summarized in this article, hoping to provide ideas for the treatment of glaucoma in the future.http://dx.doi.org/10.1155/2024/9978312 |
spellingShingle | Yasha Zhou Zhenxin Liu Wenyong Gao Yijing Yang Qinghua Peng Hanyu Tan Pathological Mechanism and Clinical Therapy Progress of Schlemm’s Canal Journal of Ophthalmology |
title | Pathological Mechanism and Clinical Therapy Progress of Schlemm’s Canal |
title_full | Pathological Mechanism and Clinical Therapy Progress of Schlemm’s Canal |
title_fullStr | Pathological Mechanism and Clinical Therapy Progress of Schlemm’s Canal |
title_full_unstemmed | Pathological Mechanism and Clinical Therapy Progress of Schlemm’s Canal |
title_short | Pathological Mechanism and Clinical Therapy Progress of Schlemm’s Canal |
title_sort | pathological mechanism and clinical therapy progress of schlemm s canal |
url | http://dx.doi.org/10.1155/2024/9978312 |
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