Autophagy activation alleviates annulus fibrosus degeneration via the miR-2355-5p/mTOR pathway
Abstract Background Intervertebral disc degeneration disease (IVDD) is a major cause of disability and reduced work productivity worldwide. Annulus fibrosus degeneration is a key contributor to IVDD, yet its mechanisms remain poorly understood. Autophagy, a vital process for cellular homeostasis, in...
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Main Authors: | Zilin Yu, Chunyang Fan, Yubo Mao, Xiexing Wu, Haiqing Mao |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Journal of Orthopaedic Surgery and Research |
Online Access: | https://doi.org/10.1186/s13018-025-05492-x |
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