An efficient method for transgenic callus induction from Vitis amurensis petiole.

Transformation is the main platform for genetic improvement and gene function studies in plants. However, the established somatic embryo transformation system for grapevines is time-consuming and has low efficiency, which limits its utilization in functional genomics research. Vitis amurensis is a w...

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Main Authors: Tingting Zhao, Zemin Wang, Lingye Su, Xiaoming Sun, Jun Cheng, Langlang Zhang, Sospeter Karanja Karungo, Yuepeng Han, Shaohua Li, Haiping Xin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0179730&type=printable
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author Tingting Zhao
Zemin Wang
Lingye Su
Xiaoming Sun
Jun Cheng
Langlang Zhang
Sospeter Karanja Karungo
Yuepeng Han
Shaohua Li
Haiping Xin
author_facet Tingting Zhao
Zemin Wang
Lingye Su
Xiaoming Sun
Jun Cheng
Langlang Zhang
Sospeter Karanja Karungo
Yuepeng Han
Shaohua Li
Haiping Xin
author_sort Tingting Zhao
collection DOAJ
description Transformation is the main platform for genetic improvement and gene function studies in plants. However, the established somatic embryo transformation system for grapevines is time-consuming and has low efficiency, which limits its utilization in functional genomics research. Vitis amurensis is a wild Vitis species with remarkable cold tolerance. The lack of an efficient genetic transformation system for it has significantly hindered the functional identification of cold stress related genes in the species. Herein, an efficient method was established to produce transformed calli of V. amurensis. Segments of petioles from micropropagated plantlets of V. amurensis exhibited better capacity to differentiate calli than leaf-discs and stem segments, and thus was chosen as target tissue for Agrobacterium-mediated transformation. Both neomycin phosphotransferase II (NPTII) and enhanced green fluorescent protein (eGFP) genes were used for simultaneous selection of transgenic calli based on kanamycin resistance and eGFP fluorescence. Several parameters affecting the transformation efficiency were optimized including the concentration of kanamycin, Agrobacterium stains, bacterial densities, infection treatments and co-cultivation time. The transgenic callus lines were verified by checking the integration of NPTII gene into calli genomes, the expression of eGFP gene and the fluorescence of eGFP. Up to 20% of the petiole segments produced transformed calli after 2 months of cultivation. This efficient transformation system will facilitate the functional analysis of agronomic characteristics and related genes not only in V. amurensis but also in other grapevine species.
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spelling doaj-art-c0f5bd6b691841b69e63a4fbd4f34a7f2025-08-20T02:03:51ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01126e017973010.1371/journal.pone.0179730An efficient method for transgenic callus induction from Vitis amurensis petiole.Tingting ZhaoZemin WangLingye SuXiaoming SunJun ChengLanglang ZhangSospeter Karanja KarungoYuepeng HanShaohua LiHaiping XinTransformation is the main platform for genetic improvement and gene function studies in plants. However, the established somatic embryo transformation system for grapevines is time-consuming and has low efficiency, which limits its utilization in functional genomics research. Vitis amurensis is a wild Vitis species with remarkable cold tolerance. The lack of an efficient genetic transformation system for it has significantly hindered the functional identification of cold stress related genes in the species. Herein, an efficient method was established to produce transformed calli of V. amurensis. Segments of petioles from micropropagated plantlets of V. amurensis exhibited better capacity to differentiate calli than leaf-discs and stem segments, and thus was chosen as target tissue for Agrobacterium-mediated transformation. Both neomycin phosphotransferase II (NPTII) and enhanced green fluorescent protein (eGFP) genes were used for simultaneous selection of transgenic calli based on kanamycin resistance and eGFP fluorescence. Several parameters affecting the transformation efficiency were optimized including the concentration of kanamycin, Agrobacterium stains, bacterial densities, infection treatments and co-cultivation time. The transgenic callus lines were verified by checking the integration of NPTII gene into calli genomes, the expression of eGFP gene and the fluorescence of eGFP. Up to 20% of the petiole segments produced transformed calli after 2 months of cultivation. This efficient transformation system will facilitate the functional analysis of agronomic characteristics and related genes not only in V. amurensis but also in other grapevine species.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0179730&type=printable
spellingShingle Tingting Zhao
Zemin Wang
Lingye Su
Xiaoming Sun
Jun Cheng
Langlang Zhang
Sospeter Karanja Karungo
Yuepeng Han
Shaohua Li
Haiping Xin
An efficient method for transgenic callus induction from Vitis amurensis petiole.
PLoS ONE
title An efficient method for transgenic callus induction from Vitis amurensis petiole.
title_full An efficient method for transgenic callus induction from Vitis amurensis petiole.
title_fullStr An efficient method for transgenic callus induction from Vitis amurensis petiole.
title_full_unstemmed An efficient method for transgenic callus induction from Vitis amurensis petiole.
title_short An efficient method for transgenic callus induction from Vitis amurensis petiole.
title_sort efficient method for transgenic callus induction from vitis amurensis petiole
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0179730&type=printable
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