Antiemetic activity of Sesamol possibly through serotonergic and dopaminergic receptor interaction pathways: In vivo and in silico studies

Antiemetic activity of Sesamol possibly through serotonergic and dopaminergic receptor interaction pathways: In vivo and in silico studies

Sesamol (SEL) is 3,4-methylenedioxyphenol isolated from sesame seeds. This study aimed to evaluate the antiemetic activity of SEL, supported by in vivo and in silico studies. Further, molecular docking was carried out to understand the molecular interaction between selected ligands and different rec...

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Main Authors: Touhidul Islam Tanim, Ayman M. Al-Qaaneh, Raihan Chowdhury, Md. Shimul Bhuia, Tabassum Islam, Md Showkoth Akbor, Md. Tahajul Islam, Md. Mohasin Miah, Ali Raza Ishaq, Mostafa A. Abdel-Maksoud, Mohamed A. El-Tayeb, Mohamed El-Shazly, Muhammad Torequl Islam, Heba A.S. El-Nashar
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Journal of Functional Foods
Subjects:
Antiemetic
Sesamol
Sesame seeds
Dopaminergic
In silico studies
Serotonin
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464625000441
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