Flow cytometry immune profiling of recurrent and newly diagnosed growth hormone secreting pituitary neuroendocrine tumors: comparison of two clinical cases

Flow cytometry immune profiling of recurrent and newly diagnosed growth hormone secreting pituitary neuroendocrine tumors: comparison of two clinical cases

Abstract Early detection of aggressive pituitary neuroendocrine tumors (PitNETs) remains challenging due to the absence of reliable markers that can predict disease progression. Aggressive tumors are typically identified through long-term observation. Tumor immune microenvironment (TIME) is crucial...

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Main Authors: Daria Lisina, Valeria Mazeeva, Elena Zakharova, Alyona Sorokina, Lilya Dzhemileva, Andrey Grigoriev, Vilen Azizyan, Alexandra Shutova, Ekaterina Pigarova, Larisa Dzeranova, Galina Melnichenko, Sergei Rumiantsev, Natalia Mokrysheva, Vladimir Chekhonin, Marina Loguinova
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Endocrine Disorders
Subjects:
Aggressive pituitary neuroendocrine tumors
PitNETs
Somatotropinoma
Immune microenvironment
Flow cytometry
Online Access:https://doi.org/10.1186/s12902-025-01865-9
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https://doi.org/10.1186/s12902-025-01865-9

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