Primary and Metastatic Pancreatic Ewing Sarcomas: A Case Report and Review of the Literature

Ewing sarcomas are rare tumors arising mainly in the bones and the surrounding soft tissues. Primary extraosseous Ewing sarcomas have also been described in several other organs and locations other than bones, including the pancreas. These tumors have well-defined histological, immunohistochemical,...

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Main Authors: Nektarios I. Koufopoulos, Menelaos G. Samaras, Christakis Kotanidis, Konstantinos Skarentzos, Abraham Pouliakis, Ioannis Boutas, Adamantia Kontogeorgi, Magda Zanelli, Andrea Palicelli, Maurizio Zizzo, Giuseppe Broggi, Rosario Caltabiano, Anastasios I. Kyriazoglou, Dimitrios Goutas
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/14/23/2694
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author Nektarios I. Koufopoulos
Menelaos G. Samaras
Christakis Kotanidis
Konstantinos Skarentzos
Abraham Pouliakis
Ioannis Boutas
Adamantia Kontogeorgi
Magda Zanelli
Andrea Palicelli
Maurizio Zizzo
Giuseppe Broggi
Rosario Caltabiano
Anastasios I. Kyriazoglou
Dimitrios Goutas
author_facet Nektarios I. Koufopoulos
Menelaos G. Samaras
Christakis Kotanidis
Konstantinos Skarentzos
Abraham Pouliakis
Ioannis Boutas
Adamantia Kontogeorgi
Magda Zanelli
Andrea Palicelli
Maurizio Zizzo
Giuseppe Broggi
Rosario Caltabiano
Anastasios I. Kyriazoglou
Dimitrios Goutas
author_sort Nektarios I. Koufopoulos
collection DOAJ
description Ewing sarcomas are rare tumors arising mainly in the bones and the surrounding soft tissues. Primary extraosseous Ewing sarcomas have also been described in several other organs and locations other than bones, including the pancreas. These tumors have well-defined histological, immunohistochemical, and molecular characteristics. In this manuscript, we present a case of primary Ewing sarcoma of the pancreas in a 29-year-old patient, and we systematically review the literature on both primary and metastatic Ewing sarcomas of the pancreas, describing their clinicopathological characteristics. We also discuss the differential diagnosis and the treatment of this rare entity.
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spelling doaj-art-c0d1b075347b488ab2a323870e9fd12b2025-08-20T01:55:28ZengMDPI AGDiagnostics2075-44182024-11-011423269410.3390/diagnostics14232694Primary and Metastatic Pancreatic Ewing Sarcomas: A Case Report and Review of the LiteratureNektarios I. Koufopoulos0Menelaos G. Samaras1Christakis Kotanidis2Konstantinos Skarentzos3Abraham Pouliakis4Ioannis Boutas5Adamantia Kontogeorgi6Magda Zanelli7Andrea Palicelli8Maurizio Zizzo9Giuseppe Broggi10Rosario Caltabiano11Anastasios I. Kyriazoglou12Dimitrios Goutas13Second Department of Pathology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, 15772 Athens, GreeceSecond Department of Pathology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, 15772 Athens, GreeceSecond Department of Pathology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, 15772 Athens, GreeceSecond Department of Pathology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, 15772 Athens, GreeceSecond Department of Pathology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, 15772 Athens, GreeceBreast Unit, Rea Maternity Hospital, P. Faliro, 17564 Athens, GreeceThird Department of Obstetrics and Gynecology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, 15772 Athens, GreecePathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, ItalyPathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, ItalySurgical Oncology Unit, Azienda USL-IRCCS di Reggio Emilia, 42122 Reggio Emilia, ItalyDepartment of Medical and Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, 95123 Catania, ItalyDepartment of Medical and Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, 95123 Catania, ItalySecond Propaedeutic Department of Medicine, Oncology Unit, National and Kapodistrian University of Athens, Attikon University Hospital, 15772 Athens, GreeceSecond Department of Pathology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, 15772 Athens, GreeceEwing sarcomas are rare tumors arising mainly in the bones and the surrounding soft tissues. Primary extraosseous Ewing sarcomas have also been described in several other organs and locations other than bones, including the pancreas. These tumors have well-defined histological, immunohistochemical, and molecular characteristics. In this manuscript, we present a case of primary Ewing sarcoma of the pancreas in a 29-year-old patient, and we systematically review the literature on both primary and metastatic Ewing sarcomas of the pancreas, describing their clinicopathological characteristics. We also discuss the differential diagnosis and the treatment of this rare entity.https://www.mdpi.com/2075-4418/14/23/2694Ewing sarcomaprimitive neuroectodermal tumorpancreasmetastasis
spellingShingle Nektarios I. Koufopoulos
Menelaos G. Samaras
Christakis Kotanidis
Konstantinos Skarentzos
Abraham Pouliakis
Ioannis Boutas
Adamantia Kontogeorgi
Magda Zanelli
Andrea Palicelli
Maurizio Zizzo
Giuseppe Broggi
Rosario Caltabiano
Anastasios I. Kyriazoglou
Dimitrios Goutas
Primary and Metastatic Pancreatic Ewing Sarcomas: A Case Report and Review of the Literature
Diagnostics
Ewing sarcoma
primitive neuroectodermal tumor
pancreas
metastasis
title Primary and Metastatic Pancreatic Ewing Sarcomas: A Case Report and Review of the Literature
title_full Primary and Metastatic Pancreatic Ewing Sarcomas: A Case Report and Review of the Literature
title_fullStr Primary and Metastatic Pancreatic Ewing Sarcomas: A Case Report and Review of the Literature
title_full_unstemmed Primary and Metastatic Pancreatic Ewing Sarcomas: A Case Report and Review of the Literature
title_short Primary and Metastatic Pancreatic Ewing Sarcomas: A Case Report and Review of the Literature
title_sort primary and metastatic pancreatic ewing sarcomas a case report and review of the literature
topic Ewing sarcoma
primitive neuroectodermal tumor
pancreas
metastasis
url https://www.mdpi.com/2075-4418/14/23/2694
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