What do we know about the possibility of predicting the potential efficacy and safety of methotrexate, by measuring the concentration of its metabolites in rheumatoid arthritis?
Rheumatoid arthritis (RA) is characterized by a progressive course with the formation of joint deformities and the development of severe functional disorders. The most favorable conditions for changing the course of the disease emerge in the first months after its onset. Methotrexate (MTX) occupies...
Saved in:
| Main Authors: | G. I. Gridneva, E. S. Aronova, V. S. Sygyrta, A. V. Kudryavtseva, K. S. Nurbaeva |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
IMA-PRESS LLC
2020-09-01
|
| Series: | Современная ревматология |
| Subjects: | |
| Online Access: | https://mrj.ima-press.net/mrj/article/view/1037 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The relationship between the efficacy of methotrexate in rheumatoid arthritis and the achieved level of its polyglutamates in erythrocytes (pilot study)
by: G. I. Gridneva, et al.
Published: (2019-05-01) -
NEW POSSIBILITIES FOR MONITORING METHOTREXATE EFFICACY IN RHEUMATOID ARTHRITIS
by: Yu. V. Muravyev
Published: (2015-09-01) -
Analysis of the relationship between the response to methotrexate therapy and its pharmacokinetic parameters in rheumatoid arthritis. Sovremennaya Revmatologiya
by: G. I. Gridneva, et al.
Published: (2022-08-01) -
Hydroxychloroquine increases the exposure of methotrexate in plasma and red blood cells: a pharmacokinetic interaction study in rats in vivo
by: Guijie Zhang, et al.
Published: (2025-04-01) -
Therapeutic drug monitoring of methotrexate and its metabolites in the red blood cells and mononuclear cells of patients with rheumatoid arthritis
by: G. I. Gridneva, et al.
Published: (2020-11-01)