Microglia are prominent producers of inflammatory cytokines during the hyperacute phase of ischemic stroke

Abstract Current treatments for ischemic stroke focus on removing neurovascular-occluding clots but overlook the resulting neuroinflammation. Clinical trials targeting brain-infiltrating peripheral immune cells have failed to improved outcomes, leaving mechanisms of neuroinflammation poorly understo...

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Bibliographic Details
Main Authors: Joshua H. Bourne, Althea R. Suthya, Brooke J. Wanrooy, Jenny L. Wilson, Shu Wen Wen, Cameron R. Bastow, Gang Zheng, Michelle Rank, Michael J. Hickey, Connie HY Wong
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08636-1
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