Ancillary Testing in Lung Cancer Diagnosis
The pathologic diagnosis of lung cancer historically has relied primarily on morphologic features of tumors in histologic sections. With the emergence of new targeted therapies, the pathologist is called upon increasingly to provide not only accurate typing of lung cancers, but also to provide progn...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | Pulmonary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/249082 |
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| _version_ | 1832565197660749824 |
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| author | William Dubinski Natasha B. Leighl Ming-Sound Tsao David M. Hwang |
| author_facet | William Dubinski Natasha B. Leighl Ming-Sound Tsao David M. Hwang |
| author_sort | William Dubinski |
| collection | DOAJ |
| description | The pathologic diagnosis of lung cancer historically has relied primarily on morphologic features of tumors in histologic sections. With the emergence of new targeted therapies, the pathologist is called upon increasingly to provide not only accurate typing of lung cancers, but also to provide prognostic and predictive information, based on a growing number of ancillary tests, that may have significant impact on patient management. This review provides an overview of ancillary tests currently used in the pathologic diagnosis of lung cancer, with a focus on immunohistochemistry and molecular diagnostics. |
| format | Article |
| id | doaj-art-c0c1c3b2ddc84e11b06d0ab9ce179c40 |
| institution | Kabale University |
| issn | 2090-1836 2090-1844 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pulmonary Medicine |
| spelling | doaj-art-c0c1c3b2ddc84e11b06d0ab9ce179c402025-02-03T01:09:07ZengWileyPulmonary Medicine2090-18362090-18442012-01-01201210.1155/2012/249082249082Ancillary Testing in Lung Cancer DiagnosisWilliam Dubinski0Natasha B. Leighl1Ming-Sound Tsao2David M. Hwang3Department of Pathology, Toronto General Hospital, University Health Network, 200 Elizabeth Street, Toronto, ON, M5G 2C4, CanadaDepartment of Medical Oncology and Hematology, Princess Margaret Hospital, University Health Network, 610 University Avenue, Toronto, ON, M5G 2M9, CanadaDepartment of Pathology, Toronto General Hospital, University Health Network, 200 Elizabeth Street, Toronto, ON, M5G 2C4, CanadaDepartment of Pathology, Toronto General Hospital, University Health Network, 200 Elizabeth Street, Toronto, ON, M5G 2C4, CanadaThe pathologic diagnosis of lung cancer historically has relied primarily on morphologic features of tumors in histologic sections. With the emergence of new targeted therapies, the pathologist is called upon increasingly to provide not only accurate typing of lung cancers, but also to provide prognostic and predictive information, based on a growing number of ancillary tests, that may have significant impact on patient management. This review provides an overview of ancillary tests currently used in the pathologic diagnosis of lung cancer, with a focus on immunohistochemistry and molecular diagnostics.http://dx.doi.org/10.1155/2012/249082 |
| spellingShingle | William Dubinski Natasha B. Leighl Ming-Sound Tsao David M. Hwang Ancillary Testing in Lung Cancer Diagnosis Pulmonary Medicine |
| title | Ancillary Testing in Lung Cancer Diagnosis |
| title_full | Ancillary Testing in Lung Cancer Diagnosis |
| title_fullStr | Ancillary Testing in Lung Cancer Diagnosis |
| title_full_unstemmed | Ancillary Testing in Lung Cancer Diagnosis |
| title_short | Ancillary Testing in Lung Cancer Diagnosis |
| title_sort | ancillary testing in lung cancer diagnosis |
| url | http://dx.doi.org/10.1155/2012/249082 |
| work_keys_str_mv | AT williamdubinski ancillarytestinginlungcancerdiagnosis AT natashableighl ancillarytestinginlungcancerdiagnosis AT mingsoundtsao ancillarytestinginlungcancerdiagnosis AT davidmhwang ancillarytestinginlungcancerdiagnosis |