Cvill6 and Cvill7: Potent and Selective Peptide Blockers of Kv1.2 Ion Channel Isolated from Mexican Scorpion <i>Centruroides villegasi</i>

Cvill6 and Cvill7: Potent and Selective Peptide Blockers of Kv1.2 Ion Channel Isolated from Mexican Scorpion <i>Centruroides villegasi</i>

Scorpion venoms are a rich source of peptides that modulate the activity of ion channels and can serve as a new drug for channelopathies. Cvill6 and Cvill7 are two new peptides isolated from the venom of <i>Centruroides villegasi</i> with MW of 4277 Da and 4287 Da and they consist of 38...

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Bibliographic Details
Main Authors: Kashmala Shakeel, Muhammad Umair Naseem, Timoteo Olamendi-Portugal, Fernando Z. Zamudio, Lourival Domingos Possani, Gyorgy Panyi
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Toxins
Subjects:
α-KTx
<i>Centruroides villegasi</i> peptides
Kv1.2
Kv1.3
KCa3.1
patch-clampelectrophysiology
Online Access:https://www.mdpi.com/2072-6651/17/6/279
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